Morphological structure of the kidney pathology according to the renal puncture biopsy data


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Objective. a retrospective analysis of renal biopsy register data for 7 years. material and methods. a retrospective study on the results of 6387 biopsies of native kidneys performed from 2013 to 2020 at the Moscow state Scientific center on the basis of City Clinical Hospital № 52 of the Moscow Healthcare department. results. The most common indications for renal biopsy included isolated urinary syndrome and nephrotic syndrome (33.0 and 32.5% of cases), as well as newly diagnosed renal failure (27%). less commonly, a biopsy was performed for acute nephritic syndrome (3.5%) and to clarify the morphological picture of an already diagnosed systemic disease (4%). In the structure of glomerular pathology, primary glomerulopathies were detected in 51% of patients, more than half (26%) of which were cases of iga nephropathy. membranous nephropathy, idiopathic fsgs and minimal change disease were detected less commonly (10.5%, 7.5% and 7%, respectively). among secondary glomerulopathies, anca-associated vasculitis (7%) and sle (5%) prevailed, also, lymphoproliferative diseases (3.6%), in most cases represented by al-amyloidosis (2.5%); as well as kidney damage in diabetes mellitus (3.2%) and hereditary nephropathy (2.7%) were detected. Conclusion. The data obtained are consistent with the prevalence of primary glomerulopathies in the structure of kidney pathology, such as iga nephropathy, membranous nephropathy, fsgs and mcD; for rarer variants of kidney pathology, however, the results of the registries can vary significantly depending on the diagnostic criteria and indications for biopsy

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E. Stolyarevich

Moscow City Scientific and Practical Center for Nephrology and Transplant Kidney Pathology, City Clinial Hospital № 52 of the Moscow Healthcare Department; A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Email: Stolyarevich@yandex.ru
Doctor of Medical Sciences, Prof, at the Department of Nephrology FPGE, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Anatomopathologist at the Pathologoanatomic Department, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

T. Zhilinskaya

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Nephrologist at the Consultative and Diagnostic Nephrology Department, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

V. Varyasin

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

PhD in Medical Sciences, Head of the Pathologoanatomic Department of City Clinical Hospital № 52 ofthe Moscow Healthcare Department, Anatomopathologist, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

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