Morphological structure of the kidney pathology according to the renal puncture biopsy data


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. a retrospective analysis of renal biopsy register data for 7 years. material and methods. a retrospective study on the results of 6387 biopsies of native kidneys performed from 2013 to 2020 at the Moscow state Scientific center on the basis of City Clinical Hospital № 52 of the Moscow Healthcare department. results. The most common indications for renal biopsy included isolated urinary syndrome and nephrotic syndrome (33.0 and 32.5% of cases), as well as newly diagnosed renal failure (27%). less commonly, a biopsy was performed for acute nephritic syndrome (3.5%) and to clarify the morphological picture of an already diagnosed systemic disease (4%). In the structure of glomerular pathology, primary glomerulopathies were detected in 51% of patients, more than half (26%) of which were cases of iga nephropathy. membranous nephropathy, idiopathic fsgs and minimal change disease were detected less commonly (10.5%, 7.5% and 7%, respectively). among secondary glomerulopathies, anca-associated vasculitis (7%) and sle (5%) prevailed, also, lymphoproliferative diseases (3.6%), in most cases represented by al-amyloidosis (2.5%); as well as kidney damage in diabetes mellitus (3.2%) and hereditary nephropathy (2.7%) were detected. Conclusion. The data obtained are consistent with the prevalence of primary glomerulopathies in the structure of kidney pathology, such as iga nephropathy, membranous nephropathy, fsgs and mcD; for rarer variants of kidney pathology, however, the results of the registries can vary significantly depending on the diagnostic criteria and indications for biopsy

Full Text

Restricted Access

About the authors

E. S Stolyarevich

Moscow City Scientific and Practical Center for Nephrology and Transplant Kidney Pathology, City Clinial Hospital № 52 of the Moscow Healthcare Department; A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Email: Stolyarevich@yandex.ru
Doctor of Medical Sciences, Prof, at the Department of Nephrology FPGE, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Anatomopathologist at the Pathologoanatomic Department, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

T. R Zhilinskaya

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Nephrologist at the Consultative and Diagnostic Nephrology Department, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

V. V Varyasin

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

PhD in Medical Sciences, Head of the Pathologoanatomic Department of City Clinical Hospital № 52 ofthe Moscow Healthcare Department, Anatomopathologist, City Clinial Hospital № 52 of the Moscow Healthcare Department Moscow, Russia

References

  1. Iversen P., Brun C. Aspiration biopsy of the kidney. Am. J. Med. 1951;11(3):324-330. doi: 10.1016/0002-9343(51)90169-6.
  2. Walker P.D., Cavallo T., Bonsib S.M. Practice guidelines for the renal biopsy. Mod. Pathol. 2004;17(12):1555-1563. doi: 10.1038/modpathol.3800239.
  3. Chang A., Gibson I.W., Cohen A.H., Weening J.W., Jennette J.C., Fogo A.B. A position paper on standardizing the nonneoplastic kidney biopsy report. Hum. Pathol. 2012;43(8):1192-9116. doi: 10.1016/j.humpath.2012.04.009.
  4. Sethi S, Haas M., Markowitz G.S., et al. Mayo clinic/renalpathology society consensus report on pathologic classification, diagnosis, and reporting of GN. J. Am. Soc. Nephrol. 2016;27(5):1278-1287. doi: 10.1681/ASN.2015060612.
  5. Sethi S., Fervenza F.C. Standardized classification and reporting of glomerulonephritis. Nephrol. Dial. Transplant. 2019;34(2): 193-199. doi: 10.1093/ndt/gfy220.
  6. Gesualdo L., Di Palma A.M., Morrone L.F., Strippoli G.F., Schena F.P. The Italian experience of the national registry of renal biopsies. Kidney Int. 2004;66(3):890-894. doi: 10.1111/j.1523-1755.2004.00831.x.
  7. Perkowska-Ptasinska A., Bartczak A., Wagrowska-Danilewicz M., et al. Clinicopathologic correlations of renal pathology in the adult population of Poland. Nephrol. Dial. Transplant. 2017;32(Suppl. 2):ii209-ii218. doi: 10.1093/ndt/gfw365.
  8. Chiu H.F., Chen H.C., Lu K.C., Shu K.H. Distribution of glomerular diseases in Taiwan: Preliminary report of National Renal Biopsy Registry-publication on behalf of Taiwan Society of Nephrology. BMC. Nephrol. 2018;19(1):1-10. doi: 10.1186/s12882-017-0810-4.
  9. Liu Z. Nephrology in China. Nat. Rev. Nephrol. 2013;9:523-528.
  10. Maixnerova D., Jancova E., Skibova J., et al. Nationwide biopsy survey of renal diseases in the Czech Republic during the years 1994-2011. J. Nephrol. 2014;28(1):39-49. doi: 10.1007/s40620-014-0090-z.
  11. Braun N., Schweisfurth A., Lohofener C., et al. Epidemiology of glomerulonephritis in Northern Germany. Int. Urol. Nephrol. 2011;43(4):1117-1126. doi: 10.1007/s11255-011-9955-4.
  12. Simon P, Ramee M.P., Boulahrouz R., et al. Epidemiologic data of primary glomerular diseases in western France. Kidney Int. 2004;66(3):905-908. doi: 10.1111/j.1523-1755.2004.00834.x.
  13. Ganesh K, Nair R., Seethalekshmy N., et al. A study of clinical presentation and correlative histopathological patterns in renal parenchymal disease. Indian J. Nephrol. 2018;28(1):28-34. doi: 10.4103/ijn.IJN_256_16.
  14. Su S, Yu J., Wang Y., Wang Y., Li J., Xu Z. Clinicopathologic correlations of renal biopsy fi ndings from northeast China. Medicine. 2019;98:23. doi: 10.1097/MD.0000000000015880.
  15. Chang J.H., Kim D.K., Kim H.W., et al. Changing prevalence of glomerular diseases in Korean adults: A review of 20 years of experience. Nephrol. Dial. Transplant. 2009;24(8):2406-2410. doi: 10.1093/ndt/gfp091.
  16. Zhou F.D., Zhao M.H., Zou W.Z., Liu G., Wang H. The changing spectrum of primary glomerular diseases within 15 years: A survey of 3331 patients in a single Chinese centre. Nephrol. Dial. Transplant. 2009;24(3):870-876. doi: 10.1093/ndt/gfn554.
  17. Sugiyama H., Yokoyama H., Sato H., et al. Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan. Clin. Exp. Nephrol. 2011;15(4):493-503. doi: 10.1007/s10157-011-0430-4.
  18. Schena F.P. Survey of the Italian Registry of Renal Biopsies. Frequency of the renal diseases for 7 consecutive years. Nephrol. Dial. Transplant. 1997;12(3):418-426. doi: 10.1093/ndt/12.3.418.
  19. Mitwalli A.H. Glomerulonephritis in saudi arabia: a review. Saudi J. Kidney Dis. Transpl. 2000;11(4):567-576.
  20. Briganti E.M., Dowling J., Finlay M., Hill P.A., Jones C.L., Kincaid-Smith P.S., Sinclair R., McNeil J.J., Atkins R.C. The incidence of biopsy-proven glomerulonephritis in Australia. Nephrol. Dial. Transplant. 2001;16(7):1364-1367.
  21. Travers K., Martin A., Khankhel Z., Boye K.S., Lee L.J. Burden and management of chronic kidney disease in Japan: systematic review of the literature. Int. J. Nephrol. Renovasc Dis. 2013;6:1-13.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies