Clinical evaluation of uropathogen selection in vivo

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Background. Unraveling the mechanisms of bacterial gene expression in vivo that induce pathogenic properties when they are in their host will help to identify new applications in the development of antimicrobials.

Objective. Evaluation of the influence of glucose metabolism in the urinary tract (UT) on the implementation of bacteriuria manifestations.

Material and methods. A retrospective laboratory and PET/CT molecular-cellular analysis of glucose metabolism
in the bladder in conjunction with the features of the clinical manifestations of bacteriuria was carried out.

Results. New data on biosynthetic and metabolic processes that induce the ability of bacteria to various manifestations
of their presence in the human MF have been obtained

Conclusion. The selection of pathogenic properties in typical representatives of the urinary tract microbiota, which determine the clinical form of bacteriuria, may be associated with the features of glucose metabolism in the organs of the urinary system, which needs special study and clarification.

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作者简介

Vadim Berdichevsky

Tyumen State Medical University

Email: urotgmu@mail.ru

Doctor of Medical Sciences, Professor of the Department of Oncology with a Course of Urology

俄罗斯联邦, Tyumen

Boris Berdichevsky

Tyumen State Medical University

Email: urotgmu@mail.ru

Doctor of Medical Sciences, Professor, Professor of the Department of Oncology with a Course in Urology

俄罗斯联邦, Tyumen

Ekaterina Sapozhenkova

Tyumen State Medical University

Email: ekaterina_chibulaeva@mail.ru

Candidate of Medical Sciences, Associate Professor of the Department of Normal Physiology

俄罗斯联邦, Tyumen

Irina Pavlova

Medical and Sanitary Unit “Neftyanik”

Email: iraena@mail.ru

Urologist of the Department of Urology

俄罗斯联邦, Tyumen

Artem Gonyaev

Clinical Hospital “Mother and Child”

Email: a.gonyaev25@yandex.ru

Urologist

俄罗斯联邦, Tyumen

Aleksey Boldyrev

Regional Clinical Hospital № 2

Email: boldyrev.a.l@yandex.ru

Urologist

俄罗斯联邦, Tyumen

Mikhail Korabelnikov

Tyumen State Medical University

Email: urotgmu@mail.ru
俄罗斯联邦, Tyumen

Daniil Petrov

Tyumen State Medical University

编辑信件的主要联系方式.
Email: tgmu@tyumsmu.ru

Student of the Faculty of Medicine

俄罗斯联邦, Tyumen

Daria Spirina

Tyumen State Medical University

Email: tgmu@tyumsmu.ru

Student of the Faculty of Medicine

俄罗斯联邦, Tyumen

参考

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