GENOTYPING IN THE MONITORING OF ENTEROVIRUSES, PATHOGENS OF SEROUS MENINGITIS


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详细

The pathogens of enterovirus meningitis were monitored by molecular genetic methods in the Nizhny Novgorod Region in 2007-2011. Partial sequencing of a VP1 genomic region was used to investigate samples from 226 patients with serous meningitis and enterovirus-positive PCR results. The genotype of enterovirus was established in 68.14% of cases. Molecular and virological studies were used to identify 316 enteroviruses belonging to 22 types of 4 species: A (0.3%), B (98.4%), C (1%), and D (0.3%). The genetic heterogeneity, phylogeny, and specific features of molecular epidemiology of ЕСНО 30, ЕСНО 9, Coxsackie А9, and ЕСНО 6 viruses prevailing among the pathogens of enterovirus meningitis in the Nizhny Novgorod Region in the period under study were examined.

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作者简介

Liudmila GOLITSYNA

Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Email: mevirfc@rambler.ru
Nizhny Novgorod

S. FOMINA

Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Email: mevirfc@rambler.ru
Nizhny Novgorod

O. PARFENOVA

Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Email: prokaids@sinn.ru
Nizhny Novgorod

L. KLIMOVA

Center for Hygiene and Epidemiology in the Nizhny Novgorod Region

Nizhny Novgorod

N. KALASHNIKOVA

Center for Hygiene and Epidemiology in the Nizhny Novgorod Region

Email: kornnvir@mail.ru
Nizhny Novgorod

N. NOVIKOVA

Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Email: mevirfc@rambler.ru
Nizhny Novgorod

参考

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