GENOTYPING IN THE MONITORING OF ENTEROVIRUSES, PATHOGENS OF SEROUS MENINGITIS
- Authors: GOLITSYNA L.N.1, FOMINA S.G1, PARFENOVA O.V1, KLIMOVA L.L2, KALASHNIKOVA N.A2, NOVIKOVA N.A1
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Affiliations:
- Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
- Center for Hygiene and Epidemiology in the Nizhny Novgorod Region
- Issue: No 2 (2013)
- Pages: 41-45
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/276558
- ID: 276558
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Abstract
The pathogens of enterovirus meningitis were monitored by molecular genetic methods in the Nizhny Novgorod Region in 2007-2011. Partial sequencing of a VP1 genomic region was used to investigate samples from 226 patients with serous meningitis and enterovirus-positive PCR results. The genotype of enterovirus was established in 68.14% of cases. Molecular and virological studies were used to identify 316 enteroviruses belonging to 22 types of 4 species: A (0.3%), B (98.4%), C (1%), and D (0.3%). The genetic heterogeneity, phylogeny, and specific features of molecular epidemiology of ЕСНО 30, ЕСНО 9, Coxsackie А9, and ЕСНО 6 viruses prevailing among the pathogens of enterovirus meningitis in the Nizhny Novgorod Region in the period under study were examined.
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About the authors
Liudmila N. GOLITSYNA
Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
Email: mevirfc@rambler.ru
Nizhny Novgorod
S. G FOMINA
Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
Email: mevirfc@rambler.ru
Nizhny Novgorod
O. V PARFENOVA
Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
Email: prokaids@sinn.ru
Nizhny Novgorod
L. L KLIMOVA
Center for Hygiene and Epidemiology in the Nizhny Novgorod RegionNizhny Novgorod
N. A KALASHNIKOVA
Center for Hygiene and Epidemiology in the Nizhny Novgorod Region
Email: kornnvir@mail.ru
Nizhny Novgorod
N. A NOVIKOVA
Academician I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
Email: mevirfc@rambler.ru
Nizhny Novgorod
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