Causes of death in persons infected with the human immunodeficiency virus

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Objective. Assessment of the causes of lethal outcomes associated with and not associated with HIV in patients with HIV infection in the Russian Federation for the period from 2008 to 2021.

Materials and methods. The results of a multi-year special study of the causes of deaths among those infected with HIV, conducted in 2007–2022, were summarized in all regions of the country.

Results. The most common etiological cause of death associated with HIV in 2019–2021, as in previous years, was mycobacterial infection. In 2018 and 2021, the number of patients who died from pneumocystis pneumonia, lymphoproliferative diseases and multiple infections increased. Cardiovascular and gastrointestinal diseases (primarily liver cirrhosis of viral etiology), as well as external causes and oncological diseases remain the main causes of deaths not associated with HIV infection. In 2021, 6.4% of people with HIV infection died from COVID-19 infection. Among the deceased, the proportion of patients receiving antiretroviral therapy was significantly less than in the population of patients with HIV infection who were under follow-up.

Conclusion. Reducing premature deaths from HIV infection and comorbidities can be achieved by increasing the coverage of people living with HIV with antiretroviral therapy and improving the diagnosis and treatment of comorbidities.

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Sobre autores

Alexey Kravchenko

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Autor responsável pela correspondência
Email: alexey-kravtchenko@yandex.ru
ORCID ID: 0000-0001-7857-3763

Professor, МD, Leader Researcher

Rússia, Moscow

Natalia Ladnaia

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: n.ladnaya@hiv-russia.ru
ORCID ID: 0000-0003-2994-151X

Cand. Biol. Sci., Senior Researcher

Rússia, Moscow

Vadim Pokrovsky

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: pokrovsky.vad@yandex.ru
ORCID ID: 0000-0002-9514-7288

Professor, Academician of the Russian Academy of Sciences, MD, Head, Specialized Research Department of Epidemiology and Prevention of AIDS

Rússia, Moscow

Nadezhda Kozyrina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: nad-kozyrina@yandex.ru
ORCID ID: 0000-0001-5134-0054

Cand. Med. Sci., Senior Researcher

Rússia, Moscow

Oleg Yurin

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: oleg_gerald@mail.ru
ORCID ID: 0000-0003-1930-7486

МD, Leading Researcher

Rússia, Moscow

Ekaterina Sokolova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: ekaterinasokolova007@rambler.ru
ORCID ID: 0000-0002-2001-8772

Cand. Med. Sci, Researcher

Rússia, Moscow

Daria Chekryzhova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: epid@hiv-russia.ru
ORCID ID: 0000-0003-0760-8257

Epidemiologist

Rússia, Moscow

Bibliografia

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  6. Кравченко А.В., Ладная Н.Н., Козырина Н.В., Покровский В.В., Юрин О.Г., Соколова Е.В. и др. Причины летальных исходов среди лиц, инфицированных ВИЧ, в Российской Федерации в 2008–2018 гг. Эпидемиол. инфекц. болезни. Актуал. вопр. 2020; 10(3): 63–9. DOI: https://dx.doi.org/10.18565/epidem.2020.10.3.63–9 Kravchenko A.V., Ladnaia N.N., Kozyrina N.V., Pokrovsky V.V., Yurin O.G., Sokolova E.V. et al. [Causes of deaths among HIV-infected persons in the Russian Federation in 2008–2018]. Epidemiology and infectious diseases. Current items 2020; 10(3): 63–9. DOI: https://dx.doi.org/10.18565/тepidem.2020.10.3.63–9
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2. Fig. 1. The main groups of causes of deaths among HIV-infected people in the Russian Federation in 2008-2021

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3. Fig. 2. Distribution of deaths from HIV infection in 2021 by cause of death (B20-B24 according to ICD-10)

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4. Fig. 3. Distribution of HIV-infected people who died in 2021 from causes unrelated to HIV infection (А00-U10, except for В20-В24 according to ICD-10 )

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