Nosocomial pneumonia in a multidisciplinary hospital: results of a retrospective study


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Objective. To assess the incidence, risk factors, and adverse outcome of nosocomial pneumonia (NP) and the prevalence of resistant pathogens. Subjects and methods. A total of 700 medical histories of patients in the Departments of Surgery and Therapy of the hospital over 2014-2015 were retrospectively analyzed. Clinical factors, the peculiarities of a surgical intervention, the risk of unfavorable outcome, and microbiological results were analyzed. Statistical analysis was carried out using the R 3.3.2 language. Results. The incidence of NP was 17.1% (n = 120). The adverse outcome was significantly influenced by the presence of cancers (53%; p = 0.003), tracheostomy (60%; p = 6.9e-11), and the duration of mechanical ventilation (p = 4.9e-08). The prognosis was not affected by body mass index (27.0±4.7 versus 26.8 ± 5.7; p = 0.88). There was a preponderance of gram-negative flora: Ac. baumanii Carb+ 15 (31.3%), Klebsiella pneumoniae ESBL 12 (25.0%), Klebsiella pneumoniae Carb+ 6 (12.5%), and Pseudomonas aeruginosa Carb+ 10 (20.8%). Conclusion. The highest incidence of NP is noted in the departments of cancer and cardiac surgery; the risk factors for adverse outcome are cancers and the duration of mechanical ventilation.

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作者简介

M. Chukina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: machukina@gmail.com
Postgraduate Student, Department of Clinical Pharmacology and Internal Diseases 6, Bolshaya Pirogovskaya St., Build 1, Моscow 119435, Russia

M. Lukina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical Univer

Email: Mari-luk2010@yandex.ru
Assistant Lecturer, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

I. Tsarev

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: mudravr@gmail.com
Resident, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

T. Andrushchishina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: tbraeva@gmail.com
Cand. Med. Sci., Associate Professor, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

T. Morozova

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: temorozova@gmail.com
MD; Professor, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

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