Nosocomial pneumonia in a multidisciplinary hospital: results of a retrospective study


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Abstract

Objective. To assess the incidence, risk factors, and adverse outcome of nosocomial pneumonia (NP) and the prevalence of resistant pathogens. Subjects and methods. A total of 700 medical histories of patients in the Departments of Surgery and Therapy of the hospital over 2014-2015 were retrospectively analyzed. Clinical factors, the peculiarities of a surgical intervention, the risk of unfavorable outcome, and microbiological results were analyzed. Statistical analysis was carried out using the R 3.3.2 language. Results. The incidence of NP was 17.1% (n = 120). The adverse outcome was significantly influenced by the presence of cancers (53%; p = 0.003), tracheostomy (60%; p = 6.9e-11), and the duration of mechanical ventilation (p = 4.9e-08). The prognosis was not affected by body mass index (27.0±4.7 versus 26.8 ± 5.7; p = 0.88). There was a preponderance of gram-negative flora: Ac. baumanii Carb+ 15 (31.3%), Klebsiella pneumoniae ESBL 12 (25.0%), Klebsiella pneumoniae Carb+ 6 (12.5%), and Pseudomonas aeruginosa Carb+ 10 (20.8%). Conclusion. The highest incidence of NP is noted in the departments of cancer and cardiac surgery; the risk factors for adverse outcome are cancers and the duration of mechanical ventilation.

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About the authors

M. A Chukina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: machukina@gmail.com
Postgraduate Student, Department of Clinical Pharmacology and Internal Diseases 6, Bolshaya Pirogovskaya St., Build 1, Моscow 119435, Russia

M. V Lukina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical Univer

Email: Mari-luk2010@yandex.ru
Assistant Lecturer, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

I. L Tsarev

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: mudravr@gmail.com
Resident, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

T. B Andrushchishina

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: tbraeva@gmail.com
Cand. Med. Sci., Associate Professor, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

T. E Morozova

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: temorozova@gmail.com
MD; Professor, Department of Clinical Pharmacology and Internal Diseases Moscow, Russia

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