Email this article Microextraction Preconcentration of Antibacterial and Non-Steroidal Anti-Inflammatory Drugs from Liquid and Solid Samples
- Authors: Pochivalov A.S.1, Garmonov S.Y.2, Bulatov A.V.1
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Affiliations:
- St. Petersburg State University
- Kazan National Research Technological University
- Issue: Vol 14, No 1 (2024)
- Pages: 32-39
- Section: Аналитика веществ и материалов
- URL: https://journals.eco-vector.com/2227-572X/article/view/628981
- DOI: https://doi.org/10.22184/2227-572X.2024.14.1.32.39
- ID: 628981
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Abstract
A set of methods for the determination of pharmaceutical substances in biological fluids, as well as approaches for fast quality control of pharmaceutical preparations was proposed. Special attention was paid to the development of efficient methods of sample preparation, allowing to increase the throughput of pharmaceutical analysis, as well as to reduce labour costs, reduce the consumption of samples, reagents and waste generated. The analytical capabilities of microextraction methods in the analysis of pharmaceutical preparations and biomedical objects were demonstrated. It was shown that switchable hydrophilicity extractants and supramolecular solvents provide high extraction recoveries of antibacterial pharmaceutical substances from samples of complex composition. The paper also presents methods of automation of microextraction processes on the principles of flow methods.
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About the authors
Alexey S. Pochivalov
St. Petersburg State University
Author for correspondence.
Email: a.pochivalov@spbu.ru
ORCID iD: 0000-0002-5791-102X
Ph.D., Assistant at the Department of Analytical Chemistry
Russian Federation, St. PetersburgSergey Yu. Garmonov
Kazan National Research Technological University
Email: GarmonovSYu@corp.knrtu.ru
Doctor of Chemical Sciences, Professor of the Department of Analytical Chemistry, Certification and Quality Management
Russian Federation, KazanAndrey V. Bulatov
St. Petersburg State University
Email: bulatov_andrey@mail.ru
ORCID iD: 0000-0002-0526-1424
Doctor of Chemical Sciences, Professor of the Department of Analytical Chemistry
Russian Federation, St. PetersburgReferences
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