Nonresection laser uvulopalatoplasty in patients with OSA



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Relevance. The main method of treating patients with severe and moderate OSA is CPAP therapy, however, it is important to choose therapy for patients with contraindications, low compliance to CPAP therapy or rejection of it. Surgical treatment is effective when significant upper respiratory tract obstruction can be eliminated, and minimally invasive techniques are preferred. Nonresection laser uvulopalatoplasty has proven to be an effective method of treating ronchopathy. Currently, there are no studies devoted to evaluating the effectiveness of this treatment method in patients with OSA. Objective: to evaluate the efficacy, safety, and tolerability of laser nonresection uvulopalatoplasty in patients with OSA. Materials and methods. 58 patients with OSA were examined with failure or poor tolerance of CPAP therapy or lack of indications after performing laser nonresection uvulopalatoplasty according to the following plan: otorhinolaryngological examination on days 1,7,14 and 30 after surgery, thermometry, assessment of complaints, subjective sensations and pain syndrome on a visually analog scale, somnological examination, transnasal fibrolaryngoscopy with the Muller test, questionnaire. Results. The dynamics of pain syndrome and local inflammatory manifestations in the area of laser exposure increased as much as possible by the third day of the postoperative period and subsided by 7-10 days after surgery. Subjectively, all patients noted an improvement in well-being according to the results of the quality of life assessment questionnaire (SF-36), a decrease in daytime sleepiness (on the Epworth scale), as well as a decrease in the risk of developing OSA on the STOP-BANG scale and the Berlin questionnaire. According to the results of the control somnological examination in the postoperative period: in 23 patients, IAG became less than 5, in 20 patients IAG decreased by more than 50%, in 11 patients IAG decreased by less than 50%. According to the results of the somnological examination, the dynamics of 4 people was negative. Conclusion. Nonresection laser uvulopalatoplasty can be successfully used in some patients with OSA. Somnological examination in the postoperative period cannot be the only objective criterion for the effectiveness of surgical treatment of patients with OSA.

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Marina Ryabova

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: marinaryabova@mail.ru
ORCID iD: 0000-0002-6714-9454
SPIN 代码: 3951-7190

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Darya Kralina

Academician I.P. Pavlov First St. Petersburg State Medical University;
St. Petersburg State Medical Institution "City Hospital of St. George the Great Martyr"

编辑信件的主要联系方式.
Email: rogova_dasha@mail.ru
ORCID iD: 0009-0003-0160-9192
SPIN 代码: 8429-2750

Postgraduate at the Department of Otorhinolaryngology «Pavlov First Saint Petersburg State Medical University»; otorhinolaryngologist of St. Petersburg State Medical Institution "City Hospital of St. George the Great Martyr"

俄罗斯联邦, Saint Petersburg

参考

  1. Clinical guidelines for the diagnosis and treatment of obstructive sleep apnea syndrome, Russian Society of Somnologists, 2024 https://rossleep.ru/klinicheskie-rekomendaczii-po-diagnostike-i-lecheniyu-obstruktivnogo-apnoe-sna/.
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  4. Askland K., Wright L., Wozniak D R, et al. Supportive and behavioral interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnea. Cochrane Database Syst Rev. 2020; Doi.org/10.1002/14651858.CD007736.pub3.
  5. Poluektov MG. Obstructive sleep apnea. Modern concepts and role // Obesity and metabolism. – 2005. – No. 1. – pp.2-7.
  6. Ryabova MA, Kralina DO. Diagnostic significance of transnasal fibrolaryngoscopy with a Muller probe in the choice of treatment tactics in a patient with ronchopathy and obstructive sleep apnea syndrome of moderate severity. A clinical case // Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. – 2024. – Vol. 30, No. 1. – pp. 95-99. – DOI: https://doi.org/10.33848/fopr627122.
  7. Ryabova MA, Karpishchenko SA, Ulupov MYu, Faizova AR., Zinchenko A. The structure of somatic pathology in patients with ronchopathy. Scientific notes of the Pavlov Moscow State Medical University. 2023; 30(4):58–64. doi: 10.24884/1607 4181-2023-30-4-58-64.
  8. Ryabova MA, Ulupov MYu, Kralina DO, Zinchenko AV, Berdysheva VA. Evaluation of the relationship between somnological examination parameters and the results of endoscopic examination of the upper respiratory tract with the Muller test in patients with ronchopathy and obstructive sleep apnea syndrome. Otorhinolaryngology Eastern Europe. 2025; Vol. 15, No. 2: 186-195. https://doi.org/10.34883/PI.2025.15.2.029.
  9. Ryabova MA. Delayed results after laser nonresection uvulopalatoplasty / M. A. Ryabova, A. R. Faizova, E. A. Volchkov // Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. – 2023. – Vol. 29, No. 1. – pp. 28-34. – doi: 10.33848/foliorl23103825-2023-29-1-28-34. – EDN BPDDXM.
  10. Ryabova MA, Kralina DO Drug treatment of patients with ronchopathy and obstructive sleep apnea syndrome in the early period after laser nonresection uvulopalatoplasty. Pharmacology & Pharmacotherapy. 2025; 2: 10–14.
  11. doi: 10.46393/27132129_2025_2_10–14.

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