GASTRODUODENAL BLEEDING IN PATIENTS WITH CARDIAC PATHOLOGY


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Abstract

Erosive and ulcerative gastroduodenal bleeding (GDB) in patients with cardiac pathology is threatening complication, in which the mortality rate ranges from 9,6 to 80%, reaching the highest numbers of patients of elderly and senile age. The need for acceptance of pathogenetic therapy, including antiplatelet agents, nonsteroidal anti-inflammatory drugs and anticoagulants of direct action greatly complicates the treatment of erosive and ulcerative GDB, which in itself is also a threat to the life of the patient. All this dictates the need for a rational treatment strategies for these patients to minimize the threat of the death of the patients from both the GDB and from heart disease. Designed by the authors of the algorithm treatment of different variants of the GDB allowed to reduce the mortality rate to 16,2%. Treatment of patients with this comorbidity requires a differentiated approach, depending on the nature and intensity of bleeding or the threat of its recurrence in the background of the need for pathogenetic therapy of the underlying disease.

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About the authors

Lyubov Fedorovna TVERITNEVA

N.V. Sklifosovsky Research Institute of Emergency Care

Email: tverlubov@yandex.ru
MD, Leading Research Fellow of Department of Emergency Surgical Gastroenterology

Irina Mikhailovna KUZMINA

N.V. Sklifosovsky Research Institute of Emergency Care

PhD, Head of Research Emergency Department of Cardiology for Patients with Myocardial Infarction

Yelena Valerievna KLYCHNIKOVA

N.V. Sklifosovsky Research Institute of Emergency Care

PhD, Head of Scientific Clinical and Biochemical Laboratory of Emergency Methods of Investigation

Andrey Vladimirovich MIRONOV

N.V. Sklifosovsky Research Institute of Emergency Care

PhD, Head of Scientific Emergency Department of Endoscopy

Yuri Sergeevich TETERIN

N.V. Sklifosovsky Research Institute of Emergency Care

PhD, physician of Emergency Department of Endoscopy

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