Endotoxin and endothelial dysfunction in patients with heart failure


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Abstract

The article considers the rote of hyperendotoxinemia and systemic inflammation response syndrome as risk factors for the progression of chronic heart failure (CHF). The necessity of joining the gastrointestinal continuum to the existing cardiovascular continuum for expanding and deepening the possibilities of etiopathogenetic correction of CHF is substantiated. It is emphasized that chronic indolent inflammation is an important risk factor for the development of CHF and the progression of atherosclerosis against the background of elevated btood endotoxin tevets.

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About the authors

Yuri V. Konev

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Email: ukonev@rambler.ru
MD, professor, head of studies of Department of outpatient therapy

Leonid B. Lazebnik

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

MD, professor of the Department of outpatient therapy

Svetlana V. Levchenko

A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Email: sv_levchenko0list.ru
PhD, assistant professor of the Department of outpatient therapy

Leonid I. Yefremov

Moscow clinical scientific practical center

PhD, leading researcher

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