ANCA-associated systemic vasculitis in clinical practice


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Diagnosis of ANCA-associated vasculitis including lung and kidneys involvement, and laboratory signs of inflammation poses difficulty. The presence of anti-neutrophil cytoplasmic antibodies (ANCA) and the results of histological investigation confirm diagnosis of ANCA-associated vasculitis. Cyclophosphamide/ azathioprine in combination with a high dose of steroids are usually used to induce and maintain remission of systemic vasculitis. The clinical trials also showed efficacy of rituximab. The article tackles a clinical case of microscopic polyangiitis.

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作者简介

Yelena Solovianova

Nizhny Novgorod state medical academy

Email: elenas-nn@mail.ru
PhD, associate professor, V.G. Vogralik Department of hospital therapy

Nikolay Borovkov

Nizhny Novgorod state medical academy

Email: borovkov-nn@mail.ru
MD, professor, head of V.G. Vogralik Department of hospital therapy

Tatiana Maslova

N.A. Semashko Nizhny Novgorod regional clinical hospital named

head of the Department of pulmonephrology

Nataliya Lineva

N.A. Semashko Nizhny Novgorod regional clinical hospital named

head of the Department of dialysis

Anastasiya Pashchenko

N.A. Semashko Nizhny Novgorod regional clinical hospital named

doctor of the Department of pulmonephrology

参考

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