ANCA-associated systemic vasculitis in clinical practice
- Authors: Solovianova Y.N.1, Borovkov N.N.1, Maslova T.I.2, Lineva N.Y.2, Pashchenko A.D.2
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Affiliations:
- Nizhny Novgorod state medical academy
- N.A. Semashko Nizhny Novgorod regional clinical hospital named
- Issue: No 6 (2016)
- Pages: 54-61
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/277738
- ID: 277738
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Abstract
Diagnosis of ANCA-associated vasculitis including lung and kidneys involvement, and laboratory signs of inflammation poses difficulty. The presence of anti-neutrophil cytoplasmic antibodies (ANCA) and the results of histological investigation confirm diagnosis of ANCA-associated vasculitis. Cyclophosphamide/ azathioprine in combination with a high dose of steroids are usually used to induce and maintain remission of systemic vasculitis. The clinical trials also showed efficacy of rituximab. The article tackles a clinical case of microscopic polyangiitis.
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About the authors
Yelena Nikolaevna Solovianova
Nizhny Novgorod state medical academy
Email: elenas-nn@mail.ru
PhD, associate professor, V.G. Vogralik Department of hospital therapy
Nikolay Nikolaevich Borovkov
Nizhny Novgorod state medical academy
Email: borovkov-nn@mail.ru
MD, professor, head of V.G. Vogralik Department of hospital therapy
Tatiana Ivanovna Maslova
N.A. Semashko Nizhny Novgorod regional clinical hospital namedhead of the Department of pulmonephrology
Nataliya Yurevna Lineva
N.A. Semashko Nizhny Novgorod regional clinical hospital namedhead of the Department of dialysis
Anastasiya Dmitrievna Pashchenko
N.A. Semashko Nizhny Novgorod regional clinical hospital nameddoctor of the Department of pulmonephrology
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