Cytomegalovirus infection during pregnancy period

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Abstract

Cytomegalovirus infection (CMV) during pregnancy can lead to fetus intrauterine infection arising with a high risk of congenital CMV developing, which is a leading cause of irreversible neurological deficit, hearing and vision loss. Methods of preventing antenatal infection, including the use of immunological and antiviral drugs, are remaining to be actual for discussion. The article presents cases of CMV infection during pregnancy and its implementation in newborn children (both according to literature data and based on our own clinical observations). Approaches to timely diagnostics and the possibilities of CMV infection therapy, which help minimize the social consequences of the disease, are introduced.

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About the authors

Valery V. Vasiliev

Children’s Scientific and Clinical Center of FMBA of Russia; I.I. Mechnikov North-West State Medical University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: vcubed@ya.ru
ORCID iD: 0000-0002-7336-8805

MD, Dr. Sci. (Medicine), head of the Scientific and Research Department of congenital infectious diseases, professor of the Department of infectious diseases

Russian Federation, Saint Petersburg; Saint Petersburg

Ivan V. Markin

Children’s Scientific and Clinical Center of FMBA of Russia

Email: i.v.markin@mail.ru
ORCID iD: 0000-0001-9922-401X

MD, postgraduate student of the Scientific and Research Department of congenital infectious diseases

Russian Federation, Saint Petersburg

Natalia V. Rogozina

Children’s Scientific and Clinical Center of FMBA of Russia

Email: lelekin96@mail.ru
ORCID iD: 0000-0003-0968-6291

MD, PhD (Medicine), senior researcher at the Scientific and Research Department of congenital infectious diseases

Russian Federation, Saint Petersburg

Natalya V. Skripchenko

Children’s Scientific and Clinical Center of FMBA of Russia; Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of Russia

Email: snv@niidi.ru
ORCID iD: 0000-0001-8927-3176

MD, Dr. Sci. (Medicine), professor, deputy director for research, head of the Department of infectious diseases in pediatrics of the Faculty of postgraduate and continuing professional education

Russian Federation, Saint Petersburg; Saint Petersburg

References

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Supplementary files

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2. Fig. 1. Ultrasound examination of the brain of the child of the observed patient O. (2nd day of life)

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3. Fig. 2. Magnetic resonance imaging of the brain of the child of the observed patient O.

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