Clinical case: autoimmune hepatitis and primary sclerosing cholangitis overlap syndrome


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Resumo

In clinical practice, there are autoimmune overlap syndrome along with standard autoimmune liver diseases - autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC). Overlap syndrome means the presence in one patient of signs characteristic of two autoimmune diseases and, as a rule, is a combination: AIH/PBC, AIH/PSC. According to statistics, in a number of patients with AIH, the cross syndrome occurs with a frequency of no more than 10%. The article presents a case of diagnosis of overlap syndrome in a patient with a combination of AIH and PSC and ulcerative colitis.

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Sobre autores

Amina Alieva

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: amisha_alieva@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Ilda Almazova

National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of Russia

Email: almazovai@rambler.ru
PhD, doctor-teacher of the Methodological Accreditation and Simulation Center

Lyudmila Brutskaya

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; Treatment and Rehabilitation Center of the Ministry of Healthcare of Russia

Email: ludmila3to@mail.ru
head of the Department of therapy

Irina Baykova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: 1498553@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Roza Arakelyan

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: sharm@yandex.ru
student of the Faculty of medicine

Anna Salnikova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: salnickova5@mail.ru
student of the Faculty of medicine

Olga Ettinger

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: olga-oett@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Vladimir Kislyakov

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: kvadoctor@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Anna Modestova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: a.modestowa@yandex.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Tatiana Pinchuk

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: doktor2000@inbox.ru
PhD, associate professor of the Department of faculty therapy of the Faculty of pediatrics

Anna Tikhomirova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: strelka_90@inbox.ru
PhD, assistant of the Department of hospital therapy No. 2 of the Faculty of medicine

Gayane Toтolyan

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: tgg03@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Madina Kudaeva

Main Bureau of Medical and Social Expertise in the Kabardino-Balkarian Republic of the Ministry of Labour and Social Protection of Russia

Email: lyalyusha1974@mail.ru
physician for medical and social examination, therapist of the expert staff of Main Bureau of Medical and Social Expertise

Dzhannet Elmurzaeva

H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: jannet.elmurzaeva@yandex.ru
associate professor of the Department of microbiology, virology and immunology

Raziyat Kadyrova

H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: kadirova47@yandex.ru
lecturer of the highest category of Medical College

Alik Rakhaev

Main Bureau of Medical and Social Expertise in the Kabardino-Balkarian Republic of the Ministry of Labour and Social Protection of Russia; H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: alikrahaev@yandex.ru
MD, head of the expert staff of Main Bureau of Medical and Social Expertise

Ramiz Valiev

A.S. Loginov Moscow Clinical Scientific Center of the Department of Healthcare of Moscow

Email: radiosurgery@bk.ru
PhD, head of the Department of surgical oncology No.2

Igor Nikitin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; Treatment and Rehabilitation Center of the Ministry of Healthcare of Russia

Email: igor.nikitin.64@mail.ru
MD, professor, head of the Department of hospital therapy No. 2 of the Faculty of medicine

Bibliografia

  1. EASL clinical practice guidelines: Autoimmune hepatitis. J. Hepatol. 2015; 63(4): 971-1004. doi: 10.1016/j.jhep.2015.06.030
  2. Sahebjam F., Vierling J.M. Autoimmune hepatitis. Front Med. 2015; 9(2): 187-219. doi: 10.1007/s11684-015-0386-y.
  3. Aabakken L., Karlsen T.H., Albert J. et al. Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline. Endoscopy. 2017; 49(6): 588-608. doi: 10.1055/s-0043-107029.
  4. Floreani, A. Clinical course and outcome of autoimmune hepatitis/ primary sclerosing cholangitis overlap syndrome / A. Floreani et al. // Am. J. Gastroenterol. 2005. Vol. 100. P. 1516-1522.
  5. Ивашкин В.Т., Широкова Е.Н., Маевская М.В. с соавт. Клинические рекомендации Российской гастроэнтерологической ассоциации и Российского общества по изучению печени по диагностике и лечению холестаза. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2015; 2: 41-57.
  6. Подымова С.Д. Перекрестные аутоиммунные синдромы в гепатологии. Экспериментальная и клиническая гастроэнтерология. 2013; 4: 3-12.
  7. Aguilar-Najera O., Velasco-Zamora J.A., Torre A. Overlap syndromes of autoimmune hepatitis: diagnosis and treatment. Rev Gastroenterol Mex. 2015; 80(2):150-59. doi: 10.1016/j.rgmx.2015.04.001.
  8. Подзолков В.И., Драгомирецкая Н.А., Волчкова Е.В., Митрохина О.И. Перекрестные синдромы при аутоиммунных заболеваниях печени. Клиническая медицина. 2017; 10: 940-945. doi: http://dx.doi.org/10.18821/0023-2149-2017-95-10-940-945.
  9. Rossi R.E., Conte D., Massironi S. Primary sclerosing cholangitis associated with inflammatory bowel disease: an update. Eur J. Gastroenterol Hepatol. 2016; 28(2): 123-31. doi: 10.1097/meg.0000000000000532.

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