Clinical case: autoimmune hepatitis and primary sclerosing cholangitis overlap syndrome


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Abstract

In clinical practice, there are autoimmune overlap syndrome along with standard autoimmune liver diseases - autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC). Overlap syndrome means the presence in one patient of signs characteristic of two autoimmune diseases and, as a rule, is a combination: AIH/PBC, AIH/PSC. According to statistics, in a number of patients with AIH, the cross syndrome occurs with a frequency of no more than 10%. The article presents a case of diagnosis of overlap syndrome in a patient with a combination of AIH and PSC and ulcerative colitis.

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About the authors

Amina M. Alieva

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: amisha_alieva@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Ilda I. Almazova

National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of Russia

Email: almazovai@rambler.ru
PhD, doctor-teacher of the Methodological Accreditation and Simulation Center

Lyudmila A. Brutskaya

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; Treatment and Rehabilitation Center of the Ministry of Healthcare of Russia

Email: ludmila3to@mail.ru
head of the Department of therapy

Irina E. Baykova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: 1498553@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Roza A. Arakelyan

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: sharm@yandex.ru
student of the Faculty of medicine

Anna I. Salnikova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: salnickova5@mail.ru
student of the Faculty of medicine

Olga A. Ettinger

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: olga-oett@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Vladimir A. Kislyakov

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: kvadoctor@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Anna V. Modestova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: a.modestowa@yandex.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Tatiana V. Pinchuk

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: doktor2000@inbox.ru
PhD, associate professor of the Department of faculty therapy of the Faculty of pediatrics

Anna S. Tikhomirova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: strelka_90@inbox.ru
PhD, assistant of the Department of hospital therapy No. 2 of the Faculty of medicine

Gayane G. Toтolyan

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: tgg03@mail.ru
PhD, associate professor of the Department of hospital therapy No. 2 of the Faculty of medicine

Madina V. Kudaeva

Main Bureau of Medical and Social Expertise in the Kabardino-Balkarian Republic of the Ministry of Labour and Social Protection of Russia

Email: lyalyusha1974@mail.ru
physician for medical and social examination, therapist of the expert staff of Main Bureau of Medical and Social Expertise

Dzhannet A. Elmurzaeva

H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: jannet.elmurzaeva@yandex.ru
associate professor of the Department of microbiology, virology and immunology

Raziyat K. Kadyrova

H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: kadirova47@yandex.ru
lecturer of the highest category of Medical College

Alik M. Rakhaev

Main Bureau of Medical and Social Expertise in the Kabardino-Balkarian Republic of the Ministry of Labour and Social Protection of Russia; H.M. Berbekov Kabardino-Balkarian State University of the Ministry of Science and Higher Education of Russia

Email: alikrahaev@yandex.ru
MD, head of the expert staff of Main Bureau of Medical and Social Expertise

Ramiz K. Valiev

A.S. Loginov Moscow Clinical Scientific Center of the Department of Healthcare of Moscow

Email: radiosurgery@bk.ru
PhD, head of the Department of surgical oncology No.2

Igor G. Nikitin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; Treatment and Rehabilitation Center of the Ministry of Healthcare of Russia

Email: igor.nikitin.64@mail.ru
MD, professor, head of the Department of hospital therapy No. 2 of the Faculty of medicine

References

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