Fronto-occipital ratio of independent components of electroencephalogram as quantitative screening test of traumatic disease flowing

Abstract


The results of ICA (Independent Component Analysis) and LORETA (Low Resolution Electromagnetic Tomography of brain) analysis of the electroencephalogram (EEG) in posttraumatic prolonged unconscious states showed sharply increased power of independent components EEG in the frontal lobes and decreased power of independent components EEG in occipital and parietal lobes of the brain compared with healthy subjects. Our studies showed that the relative measure is more sensitive to basic pathological tendencies electrogenesis in patients in post-traumatic vegetative state and status of small-consciousness, in spite of high inter-individual variability of the EEG. A relative quantitative measure - fronto-occipital ratio of power of independent components of EEG may serve as quantitative screening test flow of traumatic disease.

N A Belyakov

Email: aidscenter@admiral.ru

O E Gurskaya

V A Ponomarev

T N Trofimova

U V Nazinkina

  1. Анохин П.К. Очерки по физиологии функциональных систем. М.: Медицина, 1974. 446 с.
  2. Гриндель О.М. Электроэнцефалограмма человека при черепно-мозговой травме. М.: Наука, 1988. 200 с.
  3. Bell A.J., Sejnowski T.J. An information-maximization approach to blind separation and blind deconvolution //Neural. Comput. Vol. 7. 1995. P. 1129-1159.
  4. Gould E. How widespread is adult neurogenesis in mammals? // Nature Rev. Newosci. 2007. Vol. 8. P. 481-88.
  5. Malceig S., Bell A.J., Jung T.P., Sejnowski T.J. Independent component analysis of electroencephalo- graphic data //Neural. Inform. Proc. System. 1996. P. 145-151.
  6. Laureys S., Lemaire C., Maquet P. et al. Cerebral metabolism during vegetative state and after recovery to consciousness // J. Neurol. Neurosurg. Psychiatry. 1999b. Vol. 67. P. 121-122.
  7. Pascual-Marqui R.D., Esslen M., Kochi K. et al. Functional imaging with low-resolution brain electromagnetic tomography (LORETA): a review // Methods Find Exp. Clin. Pharmacol. 2002. Vol. 24 (Suppl.). P. 91-95.
  8. Voss H.U., Ulu A.M., Dyke J.P. et al. Possible axonal regrowth in late recovery from the minimally conscious state // J. Clin. Invest. 2006. Vol. 116. P. 2005-2011.

Views

Abstract - 27

PlumX

Refbacks

  • There are currently no refbacks.

Copyright (c) 2010 Belyakov N.A., Gurskaya O.E., Ponomarev V.A., Trofimova T.N., Nazinkina U.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.