FULLERENECARBOXYLIC ACIDS AND PROSPECTS FOR THEIR USE IN THE CHEMISTRY OF DRUGS
- Authors: Litasova EV1, Piotrovskiy LB1
-
Affiliations:
- FSBSI “Institute of Experimental Medicine”
- Issue: Vol 18, No 2 (2018)
- Pages: 19-28
- Section: Articles
- Published: 15.06.2018
- URL: https://journals.eco-vector.com/MAJ/article/view/10915
- DOI: https://doi.org/10.17816/MAJ18219-28
- ID: 10915
Cite item
Abstract
Among the various derivatives of fullerenes, compounds containing carboxyl groups (carboxyfullerenes) occupy a prominent place. The reason is that the introduction of carboxyl groups makes it possible to obtain water-soluble derivatives of highly lipophilic fullerenes. The review deals with matters of synthesis and structure of carboxyfullerenes, the influence of the amount and structure of the addends on the solubility of the entire compound, various aspects of the usage of these compounds as independent biologically active substances and carriers for creation of various delivery systems.
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About the authors
E V Litasova
FSBSI “Institute of Experimental Medicine”
L B Piotrovskiy
FSBSI “Institute of Experimental Medicine”
References
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