Delayed development of functional interactions between cortical areas of the brain as the pathogenetic basis of residual neurological disorders in children

The article describes the results of many years of research on the development of monosimptomatic residual neurological disorders in 3-11 year old children based on cross-correlation EEG analysis. We report the data on EEG analysis in speech disorders and related disorders (stammering, general speech underde­velopment, disgraphy), in attention deficit hyperactivity disorder (ADHD), enuresis and tic disorders, as well as in combinations of the above mentioned pathologies. Based on comparative EEG analysis in over 4000 patients and healthy children, we conclude that delayed development of functional interactions between brain structures, initially caused by minimal brain disfunctions in the perinatal period, underlies the pathogenesis of children's mental disorders. The specific features of such interaction impairments and their dynamics can be clearly revealed by cross-correlation EEG analysis. This work is important since no similar analysis of chil­dren's monosimptomatic residual neurological disorders is available in literature.