Etiology of severe acute respiratory infections in Ekaterinburg in different epidemic seasons

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Abstract

BACKGROUND: Acute respiratory viral infections are ubiquitous. Part of the cases are severe and require hospital treatment.

AIM: Studying the etiology of severe acute respiratory infections in patients of Ekaterinburg hospitals in different epidemic seasons (from 2017 to 2020).

MATERIALS AND METHODS: 1,132 cases of severe acute respiratory infection were assessed. The structure of laboratory-confirmed cases was determined.

RESULTS: In the assessed seasons, the proportion of respiratory viruses in the etiological structure of severe acute respiratory infections was 56.0% on average. B/Yamagata lineage of influenza viruses was predominant in the season of 2017/2018 (23.9% from the total number of respiratory viruses), — influenza А (H1N1)pdm09 viruses were predominant in the season of 2018/2019 (27.7%), and influenza A and B viruses were identified in 2019/2020 (39.4% and 31.7%, respectively).

СONCLUSIONS: The obtained results confirm a key role of influenza viruses in the etiology of severe acute respiratory infections among the hospital patients in different epidemic seasons.

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About the authors

Evgeniya Viktorovna Lelenkova

Ekaterinburg Research Institute of Viral Infections, State Research Center of Virology and Biotechnology “Vector”

Author for correspondence.
Email: lelenkova_ev@eniivi.ru
ORCID iD: 0000-0003-2004-0977
SPIN-code: 2149-3650

Researcher of the Research Methodology Department, Epidemiologist

Russian Federation, Ekaterinburg

Alexandr Yurievich Markaryan

Ekaterinburg Research Institute of Viral Infections, State Research Center of Virology and Biotechnology “Vector”

Email: markaryan_ay@eniivi.ru
ORCID iD: 0000-0002-7286-6079
SPIN-code: 2081-9246

PhD (Biol.), Senior Researcher of the Laboratory of Respiratory Viral Infections

Russian Federation, Ekaterinburg

References

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  2. Svistunova NV, Baranova IP, Zykova OA, Fedorova OV. A comparative analysis of clinical specificities of influenza A(H1N1) and influenza в in hospitalized patients. Infectious Diseases. 2013;11(1):27–32. (In Russ.)
  3. Svyatchenko SV, Durymanov AG, Susloparov IM, et al. Severe cases of seasonal influenza in Russia in 2015–2016 and 2016–2017. Journal of Microbiology, Epidemiology Immunobiology. 2018;(1):32–39. (In Russ.) doi: 10.36233/0372-9311-2018-1-32-39
  4. Meerhoff T, Simaku A, Ulqinaku D, et al. Surveillance for severe acute respiratory infections (SARI) in hospitals in the WHO European region – an exploratory analysis of risk factors for a severe outcome in influenza-positive SARI cases. BMC Infect Dis. 2015;15:1. doi: 10.1186/s12879-014-0722-x
  5. Rukovodstvo Evropeiskogo regional’nogo byuro VOZ po dozornomu ehpidnadzoru za grippom sredi lyudei [Internet]. WHO. 2011. (In Russ.) Available from: http://www.euro.who.int/data/assets/pdffile/0003/90444/e92738R.pdf. Accessed: 07.03.2021.

Supplementary files

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1. JATS XML
2. Figure. Etiological structure of respiratory viruses in the 2017-2020 epidemic seasons

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Copyright (c) 2021 Lelenkova E.V., Markaryan A.Y.

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