RNA interference as a regulatory mechanism of genes activity in the nervous and immune systems

Abstract


The review is devoted to the research results of the RNA interference processes in the nervous and immune systems, the small RNAs structures and functions, the possibility in the use of the siRNAs and miRNAs in the human disease therapy, and also - to the several problems connected with analysis of the siRNAs systems particularity functioning in different organisms, nature of the signals for dsRNAs appearance, technologic approaches to the RNAi targets screening.

T B Kazakova

Research Institute of Experimental Medicine of the RAMS, St. Petersburg

E A Korneva

Research Institute of Experimental Medicine of the RAMS, St. Petersburg

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