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Importance cytomorphologic neutrophiles changes of peripheral blood in diagnostics local epilepsy
- Authors: Selivanov EA1,2,3, Lobzin SV1,2,3, Dyskin DE1,2,3, Kuznetsov AM1,2,3, Vasilenko AV1,2,3, Asyamov KV1,2,3
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Affiliations:
- Russian Institute of Hematology, St. Petersburg
- Medical Academy of Postgraduate Studies, St. Petersburg
- Military Medical Academy, St. Petersburg
- Issue: Vol 9, No 3 (2009)
- Pages: 74-77
- Section: Articles
- URL: https://journals.eco-vector.com/MAJ/article/view/9371
- DOI: https://doi.org/10.17816/MAJ9374-77
- ID: 9371
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Abstract
Clinical, computerized-tomography and cytomorphologic studies of peripheral blood were carried out at 241 human. 102 patients with local epilepsy were entered into analysed group. 61 patients without epileptic seizures entered into comparative group. 35 practical healthy humans were included into the control group. At cytomorphologic study the definite changes of peripheral blood neutrophiles in analysed group of patients with local epilepsy. Comparative analysis of results of the clinical, EEG and cytomorphologic studies in analysed group of patients with local epilepsy established, that changes at EEG were meat more frequently. Large equivalent at comparative analysis of results of the MRI and cytomorphologic studies in analysed group of patients with local epilepsy was established. Structural neutrophiles changes can be consider as specific marker for local epilepsy and other paroxysmal seizures of epileptical nature, that presents a new perspective diagnostic direction.
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About the authors
E A Selivanov
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
S V Lobzin
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
D E Dyskin
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
A M Kuznetsov
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
A V Vasilenko
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
K V Asyamov
Russian Institute of Hematology, St. Petersburg; Medical Academy of Postgraduate Studies, St. Petersburg; Military Medical Academy, St. Petersburg
References
- Абрамов М.Г. Гематологический атлас. М.: Медицина, 1979.280 с.
- Афанасьев Ю.И., Юрина НА., Котовский Е.Ф. и др. Гистология. М.: Медицина, 1999. 744 с.
- Гартнер Л.П., Хайатт Д.Л. Цветной атлас по гистологии. М.: Логосфера, 2008. 480 с.
- Гусаров В.Г. Сравнительное клинико-иммунологическое исследование больных эпилепсией различного возраста: Автореф. дис.. канд. мед. наук. М., 1970.21 с.
- Кузник Б.И., Максимова О.Г. Общая гематология: гематология детского возраста. Ростов н/Д: Феникс, 2007. 573 с.
- Лапина Е.Ю. Клинико-функциональные аспекты симптоматической эпилепсии: Автореф. дис.. канд. мед. наук. Новосибирск, 2007. 21 с.
- Одинак М.М., Дыскин ДЕ. Эпилепсия. СПб., 1997. 233 с.
- Одинак М.М., Лобзин СВ., Дыскин Д.Е. и др. Локально обусловленная эпилепсия: корреляции клинико-электроэнцефалографического и нейровизуализационного исследований с цитоморфологическими изменениями в периферической крови // Тезисы докл. Всерос. научно-практ. конф. «Поленов-ские чтения». СПб., 2009.
- Поздняков B.C. Регуляция некоторых гемодинамических показателей в различных стадиях эпилептического процесса: Автореф. дис.. д-ра мед. наук. М., 1975.22 с.
- Худгариан М.В., Меграбян АА. Эффект карбоната лития на лимфоциты при эпилепсии. // Журн. невропатол. психиатрии им. СС Корсакова. 1987. Т. 87 (6). С. 863-866.
- Henkel К.А., Swenson C.S., Richardson В., Common R. Morphology, cytochemical staining and ultrustructural characteristics of reindeer (Rangifer tarandus) leucocytes // Vet. Clin. Pathol. 1999. Vol. 28 (1). P. 815.
- Laad G., Miranda M.F. Eosinophilic leukemoid reaction associated with carbamazepine hypersensitivity // Indian J. Dermatol. Venerol. Leprol. 2005. Vol. 71(1). P. 35-37.
- Tomonori Nakazato, Morihiko Sagawa, Kenji Yamato et al. Myeloperoxidase Is a Key Regulator of Oxidative Stress - Mediated Apoptosis in Myeloid Leukemic Cells // Clin. Cancer Res. 2007. Vol. 13. P. 5436-5445.
- Tvedten H., Riihimaki M. Hypersegmentation of equine neutrofils //Vet. Clin. Pathol. 2007. Vol. 36 (1). P. 4-5.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).