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DISTRIBUTION OF PGP 9.5-IMMUNOPOSITIVE NERVE FIBERS IN HUMAN HEART
- Authors: Chumasov EI1, Petrova ES1, Sukhorukova EG1, Korzhevsky DE1
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Affiliations:
- Research Institute of Experimental Medicine, North-West Branch of the Russian Academy of Medical Sciences
- Issue: Vol 13, No 1 (2013)
- Pages: 61-66
- Section: Articles
- URL: https://journals.eco-vector.com/MAJ/article/view/9826
- DOI: https://doi.org/10.17816/MAJ13161-66
- ID: 9826
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Abstract
Using immunohistochemical reaction for PGP 9.5, three nerve plexuses were found in the anterior wall of the left ventricle of man. The first is represented by nerve trunks from myelinated and non-myelinated fibers and non-fleshy myelinated fibers and is located in the ventricular epicardium. The nerve fibers of the trunks penetrate the myocardium. They form a second plexus. It has a high density and consists of PGP 9.5 — positive preterminal and terminal fibers. Supporting cells accompany them. Specialized nerve terminations are located between cardiomyocytes and capillaries. Third plexus is localized in the endocardium. Its preterminal and terminal branches are located directly under the endothelium. They occupy a large area on the border with the cavity of the left ventricle. Based on the fact that the described plexus includes PGP 9.5 and some morphological criteria (presence of characteristic nerve fibers arborization, the presence of specialized nerve endings and supporting cells), it is concluded that all three nerve plexuses are the afferent sensory apparatus of the left ventricle of the human heart. The function of these receptors is discussed.
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About the authors
E I Chumasov
Research Institute of Experimental Medicine, North-West Branch of the Russian Academy of Medical Sciences
Email: iemmorphol@yandex.ru
E S Petrova
Research Institute of Experimental Medicine, North-West Branch of the Russian Academy of Medical Sciences
E G Sukhorukova
Research Institute of Experimental Medicine, North-West Branch of the Russian Academy of Medical Sciences
D E Korzhevsky
Research Institute of Experimental Medicine, North-West Branch of the Russian Academy of Medical Sciences
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).