ABSENCE EPILEPSY: MECHANISMS OF HYPERSYNCHRONIZATION OF NEURONAL NETWORKS



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Abstract

Peculiarities of neurological manifestations of absence epilepsy and supported mechanisms of onset, development and termination of absence seizures are described. Clinical observations in patients with absence seizures and experimental data on genetic animal models are considered and the evidences point out the leading part of thalamocortical system in initiation and maintenance of seizure activity. A comparison of antiepileptic drugs using treatment of absence epilepsy is present.

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About the authors

A B Volnova

St.-Petersburg State University

Email: anna_neuro@yahoo.com
St.-Petersburg, Russia

D N Lenkov

Nevsky centre of scientific cooperation

St.-Petersburg, Russia

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