Morphological markers in skin basal cell carcinoma prognosis

Abstract


The morphological and immunohistochemical study using p53, Ki-67, bcl-2, E-cadherin, CK8, CK19, VEGF, collagen IV, vimentin, desmin, CD4, CD8, CD68, CD31 in 47.skin basal-cell carcinomas (SBCC) was carried out to reveal the diversity between various types of the tumor. The clinical course of the SBCC strongly depends on the topographical kind, proliferative activity and stromal reactions. The prognostic value of these morphological markers is discussed.

N M Anichkov

Mechnikov State Academy of Medicine, St. Petersburg

I N Chuprov

Medical Academy of Postgraduate Edication, St. Petersburg

Email: igorchuprov@gmail.com

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