Studies of the cerebral blood flow and metabolism in ischemic disease of the brain

Improvement of methods for diagnosis and treatment of ischemic insults is one of the most urgent problems in clinical medicine. It is due to a wide spread and trend to acute stroke (AS). According to WOS data the lethal outcome, occurred as a result of insult, makes the second place in mortality structure not only among old people but among those who are at a working ability age (40-60 y. o.) Besides, inability level in a year after the AS makes 68-82%. In Russia the rate of ischemic insult morbidity reaches 600 cases per 100 000 of citizens and it is yearly increased by 6, 5%. Success in surgical treatment for this disease depends on detection of indications for surgical intervention which are featured by new technique facilities for determining volumetric cerebral blood flow and metabolism in the area of ischemic strokes. Methods of radionuclide diagnosis were used: single photon emission CT, positron emission tomography and proton magnetic resonance spectroscopy. Based on these studies 4 areas of disorders in regional blood flow and metabolism were revealed.