Mediators of immune responses in cerebrospinal fluid with viral infections of central nervous system
- Authors: Zheleznikova GF1, Skripchenko NV1, Lobzin YV1
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Affiliations:
- Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia, St. Petersburg
- Issue: Vol 11, No 4 (2011)
- Pages: 78-85
- Section: Articles
- URL: https://journals.eco-vector.com/MAJ/article/view/10039
- DOI: https://doi.org/10.17816/MAJ11478-85
- ID: 10039
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Abstract
The revue includes contemporary information about the immune factors in cerebrospinal fluid (CSF) of patients with viral infections of central nervous system (CNS). The CSF concentrations of immunoglobulins, complement components, virus-specific antibodies, and inflammation mediators reflect their pathogenetic role in infection, that allows to use these parameters for dyagnostic improvement, course of disease prognosis, and in therapy monitoring. Detection in CSF of cytokines and chemokines, that are reflecting peculiarities of system and local immune responses in infection course, is especially clinically significant.
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About the authors
G F Zheleznikova
Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia, St. Petersburg
Email: zheleznikova.galina@gmail.com
N V Skripchenko
Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia, St. Petersburg
Y V Lobzin
Research Institute of Children Infections of the Federal Medico-Biological Agency of Russia, St. Petersburg
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