Абсорбция, распределение, метаболизм и экскреция наноструктур углерода

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Аннотация

Взаимодействие любого вещества с организмом определяется несколькими параметрами, а именно: его проникновением, распределением, трансформацией и выведением, другими словами свойствами ADME (absorption, distribution, metabolism and excretion). Естественно, это в полной мере относится и к такому классу соединений, как углеродные наноструктуры. В основном они образованы sp2-гибридизированными атомами углерода (за исключением наноалмазов, образованных sp3-гибридизированными атомами). Однако по свойствам они заметно отличаются друг от друга. Рассмотрению этих различий посвящен данный обзор, в котором рассмотрены фуллерены, наноонионы, углеродные нанотрубки, углеродные нанохорны, графен и его производные, а также наноалмазы.

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Елена Викторовна Литасова

Институт экспериментальной медицины

Email: llitasova@mail.ru
ORCID iD: 0000-0002-0999-8212
SPIN-код: 5568-8939

канд. биол. наук

Россия, Санкт-Петербург

Виктор Владимирович Ильин

Институт экспериментальной медицины

Email: victor.iljin@mail.ru
ORCID iD: 0000-0002-1012-7561
SPIN-код: 5559-8089

канд. хим. наук

Россия, Санкт-Петербург

Левон Борисович Пиотровский

Институт экспериментальной медицины

Автор, ответственный за переписку.
Email: levon-piotrovsky@yandex.ru
ORCID iD: 0000-0001-8679-1365
SPIN-код: 2927-6178

д-р биол. наук, профессор

Россия, Санкт-Петербург

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