About the Influence of Silver Nanoparticles on Living Organisms Physiology

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Abstract

The production and properties of silver-containing products currently attract increasing attention due to the unique properties of silver. Specific properties of silver are considerably amplified when it is dispersed to the form of nanosized particles. Silver nanoparticles are several times more active than its other forms and many antibiotic and biocidal products. At the same time nanoparticles can more easily penetrate the protective barriers of living organisms and get directly into their tissues and organs. To be assured of safety of silver nanoproducts for human health and environment, it is necessary to study the influence of silver nanoparticles on the physiology of living organisms. This paper presents experimental data on effect of two nanosilver preparations (poviargol and argovit) on laboratory mice. Investigated preparations were characterized by transmission electron microscopy. It was established that morphological express control of peripheral blood and biochemical analysis of blood serum of living organisms can serve for purposes of primary monitoring of the pathological conditions caused by silver nanoparticles.

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About the authors

Orkhan А Zeinalov

Company “SK&FF” Ltd

Author for correspondence.
Email: office@skiff-pharm.ru
PhD, Chief Specialist Russian Federation

Svetlana P Kombarova

Company “SK&FF” Ltd

Email: kombarsv@rambler.ru
PhD, Senior Researcher Russian Federation

Dmitry V Bagrov

Lomonosov Moscow State University

Email: dbagrov@gmail.com
PhD, Researcher at the Department of Bioengineering Russian Federation

Mariya A Petrosyan

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: mariya@labpharm.spb.ru
PhD, Senior Researcher at the Laboratory of Pharmacology Russian Federation

Gulrukhsor H Tolibova

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: gulyatolibova@yandex.ru
PhD, MD, Senior Researcher Russian Federation

Alexey V Feofanov

Lomonosov Moscow State University

Email: avfeofanov@yandex.ru
Dr. Sci., Professor at the department of bioengineering Russian Federation

Konstantin V Shaitan

Lomonosov Moscow State University

Email: shaytan49@yandex.ru
Prof., Dr. Sci., Professor at the department of bioengineering Russian Federation

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Copyright (c) 2016 Zeinalov O.А., Kombarova S.P., Bagrov D.V., Petrosyan M.A., Tolibova G.H., Feofanov A.V., Shaitan K.V.

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