About the Influence of Silver Nanoparticles on Living Organisms Physiology

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Abstract


The production and properties of silver-containing products currently attract increasing attention due to the unique properties of silver. Specific properties of silver are considerably amplified when it is dispersed to the form of nanosized particles. Silver nanoparticles are several times more active than its other forms and many antibiotic and biocidal products. At the same time nanoparticles can more easily penetrate the protective barriers of living organisms and get directly into their tissues and organs. To be assured of safety of silver nanoproducts for human health and environment, it is necessary to study the influence of silver nanoparticles on the physiology of living organisms. This paper presents experimental data on effect of two nanosilver preparations (poviargol and argovit) on laboratory mice. Investigated preparations were characterized by transmission electron microscopy. It was established that morphological express control of peripheral blood and biochemical analysis of blood serum of living organisms can serve for purposes of primary monitoring of the pathological conditions caused by silver nanoparticles.

Orkhan А Zeinalov

Company “SK&FF” Ltd

Author for correspondence.
Email: office@skiff-pharm.ru

Russian Federation PhD, Chief Specialist

Svetlana P Kombarova

Company “SK&FF” Ltd

Email: kombarsv@rambler.ru

Russian Federation PhD, Senior Researcher

Dmitry V Bagrov

Lomonosov Moscow State University

Email: dbagrov@gmail.com

Russian Federation PhD, Researcher at the Department of Bioengineering

Mariya A Petrosyan

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: mariya@labpharm.spb.ru

Russian Federation PhD, Senior Researcher at the Laboratory of Pharmacology

Gulrukhsor H Tolibova

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: gulyatolibova@yandex.ru

Russian Federation PhD, MD, Senior Researcher

Alexey V Feofanov

Lomonosov Moscow State University

Email: avfeofanov@yandex.ru

Russian Federation Dr. Sci., Professor at the department of bioengineering

Konstantin V Shaitan

Lomonosov Moscow State University

Email: shaytan49@yandex.ru

Russian Federation Prof., Dr. Sci., Professor at the department of bioengineering

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Copyright (c) 2016 Zeinalov O.А., Kombarova S.P., Bagrov D.V., Petrosyan M.A., Tolibova G.H., Feofanov A.V., Shaitan K.V.

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