Email this article Analysis of the controlled essential hypertension’s pharmacotherapy in general practice
- Authors: Slobodyanyuk A.L.1, Kupaev V.I.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 27, No 3 (2023)
- Pages: 13-21
- Section: Original studies
- URL: https://journals.eco-vector.com/RFD/article/view/456845
- DOI: https://doi.org/10.17816/RFD456845
- ID: 456845
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Abstract
BACKGROUND: Arterial hypertension is a common cardiovascular disease that requires constant monitoring by a doctor of drug therapy to achieve the target blood pressure level.
AIM: To analyze pharmacotherapy of essential hypertension in patients, who have achieved a controlled course of the disease.
MATERIALS AND METHODS: In this study 274 patients with controlled course of stage 2 arterial hypertension and no comorbidities were recruited. Blood pressure indicators, anthropometric data, results of laboratory and instrumental studies, the volume of drug therapy for hypertension were analyzed.
RESULTS: We analyzed 543 drug prescriptions for 274 patients with stage II hypertension. In 97 (35.3%) patients only one drug was prescribed, in 112 (40.7%) — two drugs, in 46 (16.7%) — three drugs from various pharmacological groups, among which monodrugs were in the lead: angiotensin-converting-enzyme inhibitors — 31.86%, cardioselective β-blockers — 23%, angiotensin 2 receptor blockers — 9.3%. Combined drugs were present in 18.4% of general doctors’ prescriptions. Fixed forms of combined antihypertensive drugs were taken by only 50 (18.4%) patients. To prevent cardiovascular complications of arterial hypertension, 75 (26%) patients were prescribed statins (atorvastatin or rosuvastatin) and 56 (19.5%) — antiplatelet monotherapy with Cardiomagnyl, Thrombo ACC or clopidogrel.
CONCLUSIONS: To achieve the target blood pressure level and control arterial hypertension in patients with stage II hypertension, general practitioners used all main
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About the authors
Anatolii L. Slobodyanyuk
Samara State Medical University
Email: a.l.slododjanjuk@samsmu.ru
ORCID iD: 0000-0002-2712-4199
md, cand. sci. (med.), assistant professor
Russian Federation, 89 Chapaevskaya St., Samara, 443099Vitalii I. Kupaev
Samara State Medical University
Author for correspondence.
Email: v.i.kupaev@samsmu.ru
ORCID iD: 0000-0003-2639-0003
md, dr. sci. (med), professor
Russian Federation, 89 Chapaevskaya St., Samara, 443099References
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