Evaluation of antigenotoxic effects of juices of plants Chelidonium majus L., Plantago major L. и Tussilago farfara L.



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Abstract

The antigenotoxic effects of juices of three medicinal plants, Chelidonium majus L., Plantago major L. and Tussilago farfara L. has been studied in two bacterial tests — SOS chromotest and Rec assay. Antigenotoxic effect was determined against known genotoxic substances — nalidixic acid in SOS chromotest and furacilin in Rec assay. Preparations obtained from the leaves of Ch. majus L. exhibited significant antigenotoxic effect in both the SOS chromotest and the Rec assay. It was shown that dilution of the herb juice of T. farfara L resulted in high bioantimutagenic activity in SOS chromotest. P. major L. preparations did not display statistically significant antigenotoxic activity in the both tests used. Possible mechanisms of antigenotoxic effects of Ch. majus L. and T. farfara L. plants obtained are discussed.

About the authors

Diana G Fatykhova

Kazan University, Kazan, Tatarstan Republic, RF

Email: fadi@bk.ru

Nazira S Karamova

Kazan University, Kazan, Tatarstan Republic, Russia

Email: nskaramova@mail.ru

Yoldyz R Abdrahimova

Kazan University, Kazan, Tatarstan Republic, RF

Email: yoldez.abdrahimova@ksu.ru Russia, Kazan

Olga N Ilinskaya

Kazan University, Kazan, Tatarstan Republic, RF

Email: Olga.Ilinskaya@ksu.ru

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Copyright (c) 2010 Fatykhova D.G., Karamova N.S., Abdrahimova Y.R., Ilinskaya O.N.

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