DNA Repeats in Bacterial Genome and Intracellular Activity of Homologous Recombinase



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Abstract

In present work distribution of perfect direct and inverted repeats in a set of bacterial genomes was analysed. Complementary cumulative distribution functions of repeat frequency for 36 bacterial strains are nonrandom and have certain characteristic features. Inverse relation of direct repeats frequency to recombinogenic activity is shown for reference E. сoli К-12 strain and P. aeruginosa strain with hyperrecombinogenic RecA protein. In general, direct repeat frequency is higher in nonpathogenic strains than that in pathogens. 

About the authors

Andrey V Ilatovsky

B.P. Konstantinov Nuclear Physics Institute, Gatchina, Leningrad Oblast, RF

Email: Andrey-soap@yandex.ru; andreyi@omrb.pnpi.spb.ru

Vladislav A Lanzov

B.P. Konstantinov Nuclear Physics Institute, Gatchina, Leningrad Oblast, RF

Email: dashach066@mail.ru

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Copyright (c) 2011 Ilatovsky A.V., Lanzov V.A.

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