A study of genetic markers of human height



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Abstract

A population study of polymorphisms of EFEMP1, ZBTB38, HHIP, LCORL, ADAMTSL3, CDH13, JAZF1, IGF1R, GHSR, CABLES1, IFNG, VDR3, and IGFBP3 genes, which possibly influence human height, was carried out using PCR-RFLP. Population frequencies of alleles and genotypes for these genes were established. A correlation between the rs572169 variant of GSHR gene and male height was found . We suggest a model for prediction of human height on the basis of logistic regression method. The obtained data indicate a possibility to assess human height on the basis of genetic markers.

About the authors

Andrey S Glotov

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: anglotov@mail.ru

Elena S Vashukova

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: vi_lena@list.ru

Oleg S Glotov

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: olglotov@mail.ru д. 3

Roman V Kurilov

Saint-Petersburg State University., Saint-Petersburg, RF

Email: roma.kur@gmail.com

Irina V Tarkovskaia

Saint-Petersburg State University., Saint-Petersburg, RF

Email: irena.88@inbox.ru

Ekaterina Y Ditkina

LLC BioGlot, St. Petersburg, RF

Email: 197341, Санкт-Петербург, Коломяжский пр., д. 28, к. 2, пом. 31-Н, лит. А

Irina V Pugacheva

LLC BioGlot, St. Petersburg, RF

Email: 197341, СПб, Коломяжский пр., д. 28, к. 2, пом. 31-Н, лит. А

Olga L Belonog

LLC BioGlot, St. Petersburg, RF

Email: 197341, СПб, Коломяжский пр., д. 28, к. 2, пом. 31-Н, лит. А

Irina A Makhrova

LLC BioGlot, St. Petersburg, RF

Email: 197341, Санкт-Петербург, Коломяжский пр., д. 28, к. 2, пом. 31-Н, лит. А

Vladimir S Pakin

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: iagmail@ott.ru

Mikhail V Aseev

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: micas@mail.ru

Tatyana E Ivashchenko

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology , Saint-Petersburg, RF

Email: tivashchenko2011@mail.ru

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Copyright (c) 2012 Glotov A.S., Vashukova E.S., Glotov O.S., Kurilov R.V., Tarkovskaia I.V., Ditkina E.Y., Pugacheva I.V., Belonog O.L., Makhrova I.A., Pakin V.S., Aseev M.V., Ivashchenko T.E.

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