The possibility of placental insufficiency prognostication in the first trimester

Abstract

Objective: prognostication of the development of placental insufficiency in the first trimester of pregnancy.

Full Text

Methods: There were 317 pregnant women examined in the first, second and third trimesters.

The method used: Ultrasound investigation with the measurement of miometry hypertonus, biometry of embryo, amnion and chorion, location of the fertilized egg; dopplerometry of uterine arteries; definition of the b-HGG level investigation of the cervical canal contents for pathogen flora.

Results: As a result of the examination 2 groups were singled out. With the first group, having a high chance of placental insufficiency, the following indexes were registered: the size of hypertonus in the area of chorion exceeded 1 sm, the fertilized egg was located in the middle and lower parts of uterus, the index of resistance was 0,991±0,085; the level of b-HGG was 2 MoM; the content of colony forming units (CFU) in the cervical canal was 10¹² and more.

The second group had a lower risk of placental insufficiency development. No hypertonus at the place of chorion attachment, fertilized egg was located in the upper parts of uterus; the index of resistance was 0,818±0,71; the level of b-HGG was 0,5-1 MoM; growth of 10^5-6 CFU was registered in the contents of the cervical canal.

In the second and third trimesters the development of placental insufficiency was diagnosed in 60% cases with the first group, and 14% - with the second.

Conclusion: complex examination in the first trimester makes it possible to prognosticate the development of placental insufficiency and promote the diminution of perinatal incidence and death rate.