Analysis of features gene polymorphism ABCB4 by NGS sequencing method in women of reproductive age with cholelithiasis

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Abstract


Analysis of ABCB4 gene in young women with cholelithiasis and relative story of gallstone disease was performed by NGS sequencing. The discovered “risk alleles” of this gene and their adverse haplotypes testify to ABCB4 participation in the development of cholelithiasis.

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About the authors

Aglaia Nikolaevna Ailamazyan

First St. Petersburg State Medical University named after Pavlov I. P

Email: iagmail@ott.ru
PhD student.

D U Semenov

First St. Petersburg State Medical University named after Pavlov I. P

Email: iagmail@ott.ru

Vladimir Semenovich Pakin

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: iagmail@ott.ru
intern department of pathology of pregnancy

M M Danilova

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: iagmail@ott.ru

Andrey Sergeevich Glotov

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: selkovsa@mail.ru
candidate of biological scientist, scientist, lab. of prenatal diagnosis of congenital and inherited diseases

Vladislav Sergeevich Baranov

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: iagmail@ott.ru
Corresponding Member of Russian Academy Sciences Chief Lab. for prenatal diagnosis of inherited and inborn disorders

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Copyright (c) 2014 Ailamazyan A.N., Semenov D.U., Pakin V.S., Danilova M.M., Glotov A.S., Baranov V.S.

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