Morphofunctional features of the fallopian tubes. Modern concepts
- Authors: Ganzhina V.S.1, Postnikova T.B.1, Bespalova O.N.1, Kogan I.Y.1
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Affiliations:
- The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 73, No 5 (2024)
- Pages: 130-138
- Section: Reviews
- Submitted: 04.06.2024
- Accepted: 06.09.2024
- Published: 04.12.2024
- URL: https://journals.eco-vector.com/jowd/article/view/633215
- DOI: https://doi.org/10.17816/JOWD633215
- ID: 633215
Cite item
Abstract
The article provides an overview of the modern literature covering the role of the fallopian tubes in reproduction.
The understanding of the anatomy and functions of the fallopian tubes has changed several times over the centuries. There is still no generally accepted opinion regarding some of the features of their structure. The normal functioning of the fallopian tubes is possible only due to the complex interaction of physical and biochemical processes occurring therein. In recent years, many discoveries have been made regarding the fallopian tubes that showed that we still do not know all the details of how this organ works. There are several basic methods for assessing the functions of the fallopian tubes, but all of them have their drawbacks and are of limited use, which is why it can sometimes be quite difficult to get a complete picture of the organ’s functioning. Modern discoveries and the introduction of new techniques into practical work can significantly expand the doctor’s capabilities in treating infertility associated with the tubal factor.
The current knowledge about the anatomical, functional and morphological features of the fallopian tubes emphasizes the importance of this organ in the implementation of the woman’s reproductive function. It is generally believed that the role of the fallopian tubes in conception is secondary and unimportant in comparison with the tasks performed by the uterus and ovaries. The importance of the fallopian tubes is most often mentioned in the literature in no more than a few paragraphs, where it is said only that the egg moves through them to the uterine cavity. However, modern research proves that complex processes and interactions occur in the organ that maintain homeostasis therein. After all, only the totality of the preserved function of each of the organs of the female reproductive system can ensure the onset and prolongation of future pregnancy.
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About the authors
Viktoria S. Ganzhina
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: ganzhina040799@gmail.com
ORCID iD: 0009-0001-5225-6484
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034
Tatyana B. Postnikova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: ptb20@mail.ru
ORCID iD: 0000-0002-8227-2629
SPIN-code: 5354-4640
MD
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034Olesya N. Bespalova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: shiggerra@mail.ru
ORCID iD: 0000-0002-6542-5953
SPIN-code: 4732-8089
MD, Dr. Sci. (Medicine)
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034Igor Yu. Kogan
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: ikogan@mail.ru
ORCID iD: 0000-0002-7351-6900
SPIN-code: 6572-6450
MD, Dr. Sci. (Medicine), Professor, Corresponding Member of the Russian Academy of Sciences
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034References
- Balandina IA, Snigireva SV. Morphometric characteristics of the external diameter of fallopian tube funnel at different periods of life in parous women. Siberian Scientific Medical Journal. 2022;42(2):33–38. EDN: LKHWBH doi: 10.18699/SSMJ20220205
- Koroleva AV, Tarasova MS, Lesovaya AA, et al. Morphology of involution of the uterus and fallopian tubes in the post-reproductive period. FORCIPE. 2019;2(S1):197–197. EDN: ZDYSMH
- Barton BE, Herrera GG, Anamthathmakula P, et al. Roles of steroid hormones in oviductal function. Reproduction. 2020;159(3):125–137. doi: 10.1530/REP-19-0189
- Hamranová N, Hocinec N, Záhumenský J, et al. Traditional and contemporary views on the functional morphology of the fallopian tubes and their importance for gynecological practice. Ceska Gynekol. 2023;88(1):33–43. doi: 10.48095/cccg202333
- Barto-clinic.ru [Internet]. Echohysterosalpingography (Echo-HSG) [cited 6 June 2024]. Available from: https://barto-clinic.ru/ekhogistero-salpingografiya-ekho-gsg
- Studopedia.ru [Internet]. Structure of walls [cited 6 June 2024]. Available from: https://studopedia.ru/4_34673_stroenie-stenok.html
- Liptáková A, Čurová K, Záhumenský J, et al. Microbiota of female genital tract – functional overview of microbial flora from vagina to uterine tubes and placenta. Physiological Research. 2022;71(Suppl 1):S21–S33. doi: 10.33549/physiolres.934960
- Bakhtiyarov KR, Raikova AA, Yudina AI. Reconstructive operations on fallopian tubes in the treatment of tubal infertility: the possibilities of restoring women’s reproductive health. Health and education in the XXI century. 2018;20(3):26–31. EDN: YSHOVB doi: 10.26787/nydha-2226-7425-2018-20-3
- Kobylyansky VI. Transport function of the fallopian tubes, its structure, mechanisms and role in the female reproductive system. Problems of reproduction. 2021;27(1):13–23. EDN: RZRRDD doi: 10.17116/repro20212701113
- Yakubova OA, Nazarova SM. Etiopathogenesis of ectopic pregnancy. Re-health journal. 2023;19(3):107–112. (In Russ.) doi: 10.24411/2181-0443
- Women secrets. The Health Care Blog [Internet]. Is it possible to get pregnant right after your period? [cited 6 June 2024]. Available from: https://womensec.ru/articles/pregnancy/planning/is-it-possible-to-get-pregnant-right-after-your-period.html
- Vitale SG, Carugno J, D’Alterio MN, et al. A new methodology to assess fallopian tubes microbiota and its impact on female fertility. Diagnostics (Basel). 2022;12(6):1375. doi: 10.3390/diagnostics12061375
- Shakirova SM, Isroilov R. Pathomorphological characteristics of the fallopian tube wall in tubal-peritoneal infertility. Economy and Society. 2022;94(3-2):964–970. EDN: NPHYIW
- Li C, Huang Y, Xie L, et al. The diagnostic value of hysterosalpingo-contrast sonography in female infertility of the fallopian tube. Pak J Med Sci. 2023;39(4):931–935. doi: 10.12669/pjms.39.4.7462
- Varga I, Kachlík D, Žišková M, et al. Lymphatic lacunae of the mucosal folds of human uterine tubes – a rediscovery of forgotten structures and their possible role in reproduction. Ann Anat. 2018;219(9):121–128. doi: 10.1016/j.aanat.2018.06.005
- Johnson J, Kim SY, Sam PK, et al. Expression and T cell regulatory action of the PD-1 immune checkpoint in the ovary and fallopian tube. Am J Reprod Immunol. 2023;89(3). doi: 10.1111/aji.13649
- Visnyaiová K, Varga I, Feitscherová C, et al. Morphology of the immune cells in the wall of the human uterine tube and their possible impact on reproduction-uterine tube as a possible immune privileged organ. Front Cell Dev Biol. 2024;12(3). doi: 10.3389/fcell.2024.1325565
- Zhang S., Dolgalev I., Zhang T., et al. Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma. Nat Commun. 2019;10(1). doi: 10.1038/s41467-019-13116-2
- Dissanayake K, Nõmm M, Lättekivi F, et al. Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue. J Mol Med (Berl). 2021;99(5):685–697. doi: 10.1007/s00109-021-02042-w
- Francés-Herrero E, Lopez R, Hellström M, et al. Bioengineering trends in female reproduction: a systematic review. Hum Reprod Update. 2022;28(6):798–837. doi: 10.1093/humupd/dmac025
- Diemer J, Hahn J, Goldenbogen B, et al. Sperm migration in the genital tract-In silico experiments identify key factors for reproductive success. PLoS Comput Biol. 2021;17(7). doi: 10.1371/journal.pcbi.1009109
- Varga I, Csöbönyeiová M, Visnyaiová K, et al. Functional morphology of the human uterine tubes in the 21st century: anatomical novelties and their possible clinical applications. Physiol Res. 2022;71(Suppl 1):S151–159. doi: 10.33549/physiolres.935036
- Barrière P, Thibault E, Jean M. Rôle de la trompe dans la fécondation [Role of Fallopian tube in fertilization]. Rev Prat. 2002;52(16):1757–1761.
- Radiopaedia [Internet] [cited 6 June 2024]. Normal hysterosalpingography. Available from: https:// radiopaedia.org/cases/normal-hysterosalpingography-1?lang=us
- Radiopaedia. Online blog for radiologosts [Internet]. Sonohysterography [cited 6 June 2024]. Available from: https://radiopaedia.org /articles/sonohysterography?lang=us
- Simedica.ru [Internet]. Pertubation [cited 6 June 2024]. Available from: https://simedica.ru/Analizy_i_diagnostika?t=pertubaciya
- Medlife05.ru [Internet]. Study of the patency of the fallopian tubes [cited 6 June 2024]. Available from: https://medlife05.ru/blog/issledovanie-prohodimosti-matochnyh-trub/
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