Email this article Borderline ovarian tumors: modern diagnostic criteria at the preoperative stage
- Authors: Tsypurdeyeva A.A.1, Protasova A.E.2, Solntseva I.A.2, Mikhelashvili L.I.2
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Affiliations:
- The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott
- The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 71, No 2 (2022)
- Pages: 61-68
- Section: Original Research
- Submitted: 04.10.2021
- Accepted: 08.02.2022
- Published: 15.04.2022
- URL: https://journals.eco-vector.com/jowd/article/view/81798
- DOI: https://doi.org/10.17816/JOWD81798
- ID: 81798
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Abstract
AIM: The aim of this study was to define and standardize the clinical and diagnostic criteria for borderline ovarian tumors at the preoperative stage.
MATERIALS AND METHODS: A retrospective analysis of 35 clinical case histories of patients with morphologically established borderline ovarian tumors has been conducted. Clinical and morphological data were analyzed: age, anamnesis, examination data, disease stage, histological study results. Laboratory parameters were assessed: CA-125 tumor marker level and ultrasound characteristics using criteria defined by IOTA, ADNEX and O-RADS groups.
RESULTS: A single cyst with a solid component was a typical ultrasound type of borderline ovarian tumors (45.71%). The application of the simple IOTA rules in regards to evaluating the formations proved possible in 100% of the cases and the formation was regarded as undefined in 62.86% of the cases. In 51.43% of the cases, the formation belonged to O-RADS 4 (10% to <50% risk of malignancy). The study of CA-125 tumor marker levels showed insufficient sensitivity, only 57.14% of patients having the parameter above the norm.
CONCLUSIONS: The application of the IOTA and O-RADS criteria allows for differentiating not only benign and malignant, but also borderline ovarian tumors, thus determining the choice of an organ-preserving treatment for patients of reproductive age.
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About the authors
Anna A. Tsypurdeyeva
The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott
Email: tsypurdeevan@mail.ru
ORCID iD: 0000-0001-7774-2094
SPIN-code: 5208-9707
MD, Cand. Sci. (Med.)
Russian Federation, Saint PetersburgAnna E. Protasova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: protasova1966@yandex.ru
ORCID iD: 0000-0001-7930-8048
MD, Dr. Sci. (Med.), Assistant Professor
Russian Federation, Saint PetersburgIrina A. Solntseva
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: protasova1966@yandex.ru
ORCID iD: 0000-0002-2692-2156
MD, Cand. Sci. (Med.)
Russian Federation, Saint PetersburgLina I. Mikhelashvili
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: lina.michelashvili@gmail.com
Russian Federation, Saint Petersburg
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