Ovarian blood flow in healthy women and patients with ovarian failure

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Objective: to investigate the relationships between ovarian blood flow, folliculogenesis and sex-steroids production during normal menstrual cycle and in women with ovarian failure

Materials and methods. 10 healthy women and 24 patients with luteal phase defect were underwent hormonal assays (estradiol, progesterone) and ultrasound examination of the uterus and ovaries with color Doppler ultrasonography of the ovarian vessels on 3 - 5, 11 -13,17-19 and 21-23 days of menstrual cycle. Also was done laparoscopy and hysteroscopy with ovary and endometrial biopsy.

Results. It was determined that in healthy women intraovarian blood flow of the ovary carrying dominant follicle was more active then one in patients with the ovarian failure throw the follicular phase. On the 21 - 23th days of menstrual cycle there was registered reduced blood supply of the corpus luteum and decreased progesterone levels in women with luteal phase defect.

Conclusions. Ovarian blood flow in patients with the ovarian failure was less than in healthy women in early follicular and luteal phases of menstrual cycle. Unsufficient blood supply of the corpus luteum is accompanied by reduced progesterone level in the serum.

About the authors

L. K. Dzhemlikhanova

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; Saint Petersburg State University

Author for correspondence.
Email: info@eco-vector.com

Department of Obstetrics and Gynecology, Faculty of Medicine

Russian Federation, Saint-Petersburg; Saint-Petersburg

E. N. Popov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; Saint Petersburg State University

Email: info@eco-vector.com

Department of Obstetrics and Gynecology, Faculty of Medicine

Russian Federation, Saint-Petersburg; Saint-Petersburg

References

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