Email this article Markers of bone remodeling in patients with surgical menopause undergoing hormone replacement therapy with Divigel
- Authors: Yureneva S.V.1,2, Smetnik V.P.1,2, Lyubimova N.V.1,2, Abaev V.M.1,2
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Affiliations:
- Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences
- Russian Cancer Research Center. N.N.Blokhina RAMS
- Issue: Vol 50, No 3 (2001)
- Pages: 70-75
- Section: Original Research
- URL: https://journals.eco-vector.com/jowd/article/view/95593
- DOI: https://doi.org/10.17816/JOWD95593
- ID: 95593
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Abstract
Twenty women with surgical menopause, 40-50 years of age, received hormonal replacement therapy with transdermic preparation Divigel during 24 months. On the background of therapy with Divigel we witnessed normalization of indeces of osteal remodeling—considerable decrease pyridinoline and deoxypyridinoline, and elevation of alkaline phosphatase. Mineral density of bone tissue in the group of patients with surgical menopause waslowerin comparison with control (p<0,01). Divigeltumedto exertprotective influence on the bone tissue inpatients with osteoporosis irrespective о f duration о f surgical menopause by the beginning of therapy.
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About the authors
S. V. Yureneva
Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences; Russian Cancer Research Center. N.N.Blokhina RAMS
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow
V. P. Smetnik
Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences; Russian Cancer Research Center. N.N.Blokhina RAMS
Email: info@eco-vector.com
Russian Federation, Moscow
N. V. Lyubimova
Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences; Russian Cancer Research Center. N.N.Blokhina RAMS
Email: info@eco-vector.com
Russian Federation, Moscow
V. M. Abaev
Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences; Russian Cancer Research Center. N.N.Blokhina RAMS
Email: info@eco-vector.com
Russian Federation, Moscow
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