Influence of Mildronatum on the “mother-placenta-fetus” system circulation with different degrees of its disorder
- Авторы: Krivtsova E.I.1, Pavlova N.G.1
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Учреждения:
- D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
- Выпуск: Том 48, № 5S (1999)
- Страницы: 91-91
- Раздел: Статьи
- Статья получена: 17.02.2022
- Статья одобрена: 17.02.2022
- Статья опубликована: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101029
- DOI: https://doi.org/10.17816/JOWD101029
- ID: 101029
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Аннотация
Objective: Investigation of the influence of Mildronatum on hemodynamics in the “mother-placenta-fetus” system with different degrees of its circulatory disorders in 21 women in the III trimester of pregnancy.
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Objective: Investigation of the influence of Mildronatum on hemodynamics in the “mother-placenta-fetus” system with different degrees of its circulatory disorders in 21 women in the III trimester of pregnancy.
Methods: Dopplerometric study of the blood flow was performed in the umbilical artery (UmA), middle meningeal artery of the fetus and uterine arteries (UtA) before and after infusion 10% solution of mildronatum in a dose of 5,0 ml.
Results: Administration of mildronatum at the I (SDR FVW UmA=3,98±0,21; IR = 0,74±0,01) and II (SDR FVW UmA = 4,1±0,29; IR = 0,75±0,01; SDR FVW UtA = 2,87±0,35; IR = 0,63±0,03) degree of the blood flow disorder resulted in normalization of feto-placental blood flow in the UtA by 9% with the II degrees of the disorder. A reliable decrease of SDR FVW in the UmA was observed (SDR FVW UmA = 7,18±1,52; IR = 0,83±0,04, SDR FVW UmA = 4,44±0,79; IR = 0,74±0,05 respectively) as well as normalization of the cerebroplacental ratio. Blood flow in the UtA did not change.
Conclusions: Mildronatum exerts favorable influence on pathological hemodynamic changes in the “mother-placenta-fetus” system, and its efficiency is maximum in cases of significant blood flow disorders.
Об авторах
E. I. Krivtsova
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
Автор, ответственный за переписку.
Email: info@eco-vector.com
Россия, St. Petersburg
N. G. Pavlova
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
Email: info@eco-vector.com
Россия, St. Petersburg
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