Influence of Mildronatum on the “mother-placenta-fetus” system circulation with different degrees of its disorder
- 作者: Krivtsova E.I.1, Pavlova N.G.1
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隶属关系:
- D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
- 期: 卷 48, 编号 5S (1999)
- 页面: 91-91
- 栏目: Articles
- ##submission.dateSubmitted##: 17.02.2022
- ##submission.dateAccepted##: 17.02.2022
- ##submission.datePublished##: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101029
- DOI: https://doi.org/10.17816/JOWD101029
- ID: 101029
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Objective: Investigation of the influence of Mildronatum on hemodynamics in the “mother-placenta-fetus” system with different degrees of its circulatory disorders in 21 women in the III trimester of pregnancy.
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Objective: Investigation of the influence of Mildronatum on hemodynamics in the “mother-placenta-fetus” system with different degrees of its circulatory disorders in 21 women in the III trimester of pregnancy.
Methods: Dopplerometric study of the blood flow was performed in the umbilical artery (UmA), middle meningeal artery of the fetus and uterine arteries (UtA) before and after infusion 10% solution of mildronatum in a dose of 5,0 ml.
Results: Administration of mildronatum at the I (SDR FVW UmA=3,98±0,21; IR = 0,74±0,01) and II (SDR FVW UmA = 4,1±0,29; IR = 0,75±0,01; SDR FVW UtA = 2,87±0,35; IR = 0,63±0,03) degree of the blood flow disorder resulted in normalization of feto-placental blood flow in the UtA by 9% with the II degrees of the disorder. A reliable decrease of SDR FVW in the UmA was observed (SDR FVW UmA = 7,18±1,52; IR = 0,83±0,04, SDR FVW UmA = 4,44±0,79; IR = 0,74±0,05 respectively) as well as normalization of the cerebroplacental ratio. Blood flow in the UtA did not change.
Conclusions: Mildronatum exerts favorable influence on pathological hemodynamic changes in the “mother-placenta-fetus” system, and its efficiency is maximum in cases of significant blood flow disorders.
作者简介
E. Krivtsova
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg
N. Pavlova
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg
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