Borderline ovarian tumors: modern diagnostic criteria at the preoperative stage

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AIM: The aim of this study was to define and standardize the clinical and diagnostic criteria for borderline ovarian tumors at the preoperative stage.

MATERIALS AND METHODS: A retrospective analysis of 35 clinical case histories of patients with morphologically established borderline ovarian tumors has been conducted. Clinical and morphological data were analyzed: age, anamnesis, examination data, disease stage, histological study results. Laboratory parameters were assessed: CA-125 tumor marker level and ultrasound characteristics using criteria defined by IOTA, ADNEX and O-RADS groups.

RESULTS: A single cyst with a solid component was a typical ultrasound type of borderline ovarian tumors (45.71%). The application of the simple IOTA rules in regards to evaluating the formations proved possible in 100% of the cases and the formation was regarded as undefined in 62.86% of the cases. In 51.43% of the cases, the formation belonged to O-RADS 4 (10% to <50% risk of malignancy). The study of CA-125 tumor marker levels showed insufficient sensitivity, only 57.14% of patients having the parameter above the norm.

CONCLUSIONS: The application of the IOTA and O-RADS criteria allows for differentiating not only benign and malignant, but also borderline ovarian tumors, thus determining the choice of an organ-preserving treatment for patients of reproductive age.

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作者简介

Anna Tsypurdeyeva

The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott

Email: tsypurdeevan@mail.ru
ORCID iD: 0000-0001-7774-2094
SPIN 代码: 5208-9707

MD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

Anna Protasova

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: protasova1966@yandex.ru
ORCID iD: 0000-0001-7930-8048

MD, Dr. Sci. (Med.), Assistant Professor

俄罗斯联邦, Saint Petersburg

Irina Solntseva

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: protasova1966@yandex.ru
ORCID iD: 0000-0002-2692-2156

MD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

Lina Mikhelashvili

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

编辑信件的主要联系方式.
Email: lina.michelashvili@gmail.com
俄罗斯联邦, Saint Petersburg

参考

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