电邮这篇文章 Dynamic laparascopy as a stage of hospital rehabilitation in patients with tubal pregnancy
- 作者: Shipitsyna Е.V.1, Novikov А.V.1, Shalepo К.V.1, Bezhenar V.F.1, Savicheva А.М.1
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隶属关系:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- 期: 卷 54, 编号 5S (2005)
- 页面: 33-34
- 栏目: Reviews
- ##submission.dateSubmitted##: 15.11.2005
- ##submission.dateAccepted##: 07.11.2021
- ##submission.datePublished##: 15.11.2005
- URL: https://journals.eco-vector.com/jowd/article/view/87218
- DOI: https://doi.org/10.17816/JOWD87218
- ID: 87218
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Objectives: Chlamydia trachomatis infection of the upper genital tract often results in pelvic inflammatory disease (PID), and its sequels include ectopic pregnancy (EP), miscarriage and tubal infertility. This study was aimed to evaluate the rate of C. trachomatis detection as well as anti-C trachomatis antibodies in women with EP.
全文:
Objectives: Chlamydia trachomatis infection of the upper genital tract often results in pelvic inflammatory disease (PID), and its sequels include ectopic pregnancy (EP), miscarriage and tubal infertility. This study was aimed to evaluate the rate of C. trachomatis detection as well as anti-C trachomatis antibodies in women with EP.
Material and methods. A total of 13 women with EP were examined. Control subjects (n=38) were drawn from pregnant women with uneventful reproductive history. Sera were analysed for anti-C. trachomatis IgG and IgA with the use of indirect solid-phase enzyme immunoassay (ImmunoComb® Chlamydia trachomatis, Orgenics, Israel). Cervical swabs from all the women, as well as biopsies taken from women with EP during surgery, were investigated for C. trachomatis making use of McCoy cell culture and polymerase chain reaction (PCR) (AmpliSens Chlamydia trachomatis, Research Institute of Epidemiology, Russia).
Results. Anti-C. trachomatis antibodies were detected in 12 of 13 women (92,3%) with EP: IgG - in all the 12 women, IgA - in 3 of them (23,1%). In 8 women (66,7%) IgG were found at high titre (>1:64). In two patients (15,4%) with ЕР C. trachomatis was detected in the cervix using PCR: in both sera from those women there were anti-C. trachomatis IgG at high titre (1:64), and in one of them IgA were also found. In none of the women was C. trachomatis detected in biopsy specimens: chlamydial infection occurring in the past may account for this fact.
In control subjects, anti-C. trachomatis IgG were detected in 10 of 38 women (26,3%), with only two of them (20%) - at high titre ( ≥1:64). IgA were found in one woman (2,6%): the cervical swab from that woman was shown to be positive for C. trachomatis.
Conclusions. The high rate of detection of anti-C. trachomatis antibodies in women with EP underlines the importance of this microorganism in the development of this condition. Presence of anti-C trachomatis antibodies, particularly at high titre, may be suggestive of C. trachomatis infection of the upper genital tract, current or previous, therefore screening for C trachomatis specific antibodies may be valuable diagnostic and prognostic tool in the management of PID.
作者简介
Е. Shipitsyna
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
А. Novikov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
К. Shalepo
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
V. Bezhenar
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
А. Savicheva
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
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