Choroidal thickness in eyes with different degrees of myopia

Cover Page

Abstract


66 healthy people (124 eyes) with different degrees of myopia and emmetropia were examined using enhanced depth imaging optical coherence tomography (EDI-OCT) using the “Spectralis OCT”. It was found that the choroid in subjects with medium and high degrees of myopia was significantly thinner than that in the control group. In the study, a negative correlation was found between the subfoveal choroidal thickness and the degree of myopia (r = -0.75, p < 0.0001). It was also found that the subfoveal choroidal thickness decreased for each diopter of myopia by approximately 18.03 μm.

Yuriy Sergeyevich Astakhov

I. P. Pavlov State Medical University of St. Petersburg

Email: astakhov73@mail.ru
MD, doctor of medical science, professor, head of the department

Svetlana Georgiyevna Belekhova

I. P. Pavlov State Medical University of St. Petersburg

Email: beleksv@yandex.ru
Postgraduate student. Department of Ophthalmology

  • Curtin B. J., Karlin D. B. Axial length measurements and fundus changes of the myopic eye // Am. J. Ophthalmol. - 1971. - Vol. 1. - P. 42-53.
  • Fujiwara T., Imamura Y., Margolis R., Slakter J. S. et al. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes // Am. J. Ophthalmol. - 2009. - Vol. 148, N 3. - P. 445-450.
  • Geitzenauer W., Hitzenberger C. K., Schmidt-Erfurth U. M. Retinal optical coherence tomography: past, present and future perspectives // Br. J. Ophthalmol. - 2011. - Vol. 95, N 2. - P. 171-177.
  • Guyer D. R., Schachat A. P., Green W. R. The choroid: structural considerations In: Ryan S. J., ed.-in-chief // Retina. Philadelphia: Elsevier Mosby. - Vol. 1. N 4. - 2006. - P. 33-34.
  • Hee M. R., Izatt J. A., Swanson E. A., Huang D., Schuman J. S., Lin C. P., Puliafito C. A., Fujimoto J. G. Optical coherence tomography of the human retina // Arch. Ophthalmol. - 1995. - Vol.113, N 3. - P. 325-332.
  • Imamura Y., Fujiwara T., Margolis R., Spaide R. F. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy // Retina. - 2009. - Vol. 28. - P. 1469-1473.
  • Margolis R., Spaide R. F. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes // Am. J. Ophthalmol. - 2009. - Vol.147, N 5. - P. 811-815.
  • Metelitsina T. I., Grunwald J. E., DuPont J. C., Ying G. S., Brucker A. J., Dunaief J. L. Foveolar choroidal circulation and choroidal neovascularization in age-related macular degeneration // Invest. Ophthalmol. Vis Sci. - 2008. - Vol. 49. - P. 358-363.
  • Povazay B., Hermann B., Unterhuber A. et al. Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients // J. Biomed. Opt. - 2007. - Vol. 12, N 4. - 041211.
  • Saw S. M., Gazzard G., Shin-Yen E. C., Chua W. H. Myopia and associated pathological complications // Ophthalmic. Physiol. Opt. - 2005. - Vol. 25. - P. 381-91.
  • Spaide R. F., Koizumi H., Pozonni M. C. Enhaced depth imaging spectral-domain optical coherence tomography // Am. J. Ophthalmol. - 2008. - Vol. 146. - P. 496-500.

Views

Abstract - 262

PDF (Russian) - 412

Cited-By


CrossRef     2 citations

  • Berry V, Pontikos N, Albarca-Aguilera M, Plagnol V, Massouras A, Prescott D, et al. A recurrent splice-site mutation in EPHA2 causing congenital posterior nuclear cataract. Ophthalmic Genetics. 2018;39(2):236. doi: 10.1080/13816810.2017.1381977
  • Hamada N, Fujimichi Y. Role of carcinogenesis related mechanisms in cataractogenesis and its implications for ionizing radiation cataractogenesis. Cancer Letters. 2015;368(2):262. doi: 10.1016/j.canlet.2015.02.017

PlumX


Copyright (c) 2013 Astakhov Y.S., Belekhova S.G.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.