Influence of vitrectomyon the progressionof wet age related macular degeneration

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Abstract


Purpose. To study the effects of vitrectomy on the course of wet age-related macular degeneration (AMD). Materials and methods. 99 patients (99 eyes) with wet AMD associated with vitreo-macular adhesion or posterior hyaloid traction were included in the study. During the first 6 months, all patients received anti-VEGF treatment according to a PRN regimen. Then, they were divided into two groups: in 45 patients vitrectomy was performed and 54 patients did not receive surgical treatment. The follow-up period duration was one year. Results. At the beginning of the study, visual acuity was 0.27 ± 0.17 in the control group, and 0.17 ± 0.15 in the treatment group. Most prominent differences in visual acuity between the two groups were observed during the first 6 months (visual acuity in the treatment group before surgery was 0.12 ± 0.1) (p < 0.01 and p < 0.001), at the same time during the following 6 follow-up months, this difference decreased (p < 0.05 and p < 0.01). 1 year from the study start, visual acuity in the control group was 0.24 ± 0.17, and 0.17 ± 0.13 in the treatment one. Conclusions. Vitrectomy surgery in patients with wet AMD in association with vitreo-macular adhesion or posterior hyaloid traction does not exacerbate the disease course, stabilizes visual functions and improves the quality of life.

Yuriy Sergeyevich Astakhov

First I. P. Pavlov State Medical University of St. Petersburg

Email: astakhov73@mail.ru
MD, doctor of medical science, professor, Department of Ophthalmology

Gassan Basharovich Shaar

First I. P. Pavlov State Medical University of St. Petersburg

Email: ghassan_shaar@mail.ru
postgraduate student, Department of Ophthalmology

Nikita Yur’yevich Dal’

First I. P. Pavlov State Medical University of St. Petersburg

Email: ndahl@yandex.ru
MD, doctor of medical science, professor, head of the department. Department of Ophthalmology

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Copyright (c) 2014 Astakhov Y.S., Shaar G.B., Dal’ N.Y.

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