The influence of vitreomacular adhesion on the pathogenesis and course of age-related macular degeneration

Cover Page


Cite item

Full Text

Abstract

This article describes the age-related changes in vitreous and different types of posterior vitreous detachment. Possible effect of normal and pathological posterior vitreous detachment (in particular vitreomacular adhesion and traction syndrome) on the age-related macular degeneration course are considered. Vitrectomy and pharmacological vitreolysis potentials in the treatment of vitreomacular adhesion are discussed.

About the authors

Nikita Yuryevich Dal

I. P. Pavlov State Medical University

Email: ndahl@yandex.ru
candidate of medical science, assistant professor, Department of Ophthalmology

Gassan Basharovich Shaar

I. P. Pavlov State Medical University

Email: ghassan_shaar@hotmail.com
postgraduate student, Department of Ophthalmology

Yuriy Sergeyevich Astakhov

I. P. Pavlov State Medical University

Email: astakhov@spmu.rssi.ru
MD, professor, head of the department of ophthalmology

Marina Mikhaylovna Lobanova

I. P. Pavlov State Medical University

Email: antaryo@gmail.com
resident, Department of Ophthalmology

References

  1. Антелава Д. Н., Пивоваров Н. Н., Садоян А. А. Первичная отслойка сетчатки. — Тбилиси. — 1986. — 159 с.
  2. Бойко Э. В., Суетов А. А., Мальцев Д. С. Отслойка задней гиалоидной мембраны: понятие, распространенность, классификации, клиника и возможные причины // Офтальмологические ведомости. — 2009. — Т. II. — Выпуск 3. — C. 39–46.
  3. Горбань А. И. Стекловидное тело в клинической офтальмологии. — Ленинград. — 1981. — 68 с.
  4. Краснов М. М., Сдобникова С. В., Федоров А. А., Столяренко Г. Е. Заднегиалоидная мембрана как структурная основа роста новообразованной ткани при пролиферативной диабетической ретинопатии // Вестник офтальмологии. — 1998. — № 3. — С. 16–20.
  5. Луковская Н. Г., Астахов Ю. С. Ретиношизис. Этиопатогенез. Диагностика. Клиника. Лечение. — СПб. — 2008. — 112 с.
  6. Сдобникова С. В. Роль удаления заднегиалоидной мембраны в трансвитреальной хирургии пролиферативной диабетической ретинопатии: Автореф. дис… канд. мед. наук. — М., 1997. — 23 с.
  7. Сдобникова С. В., Столяренко Г. Е., Федоров А. А., Марченко Н. Р. О роли заднегиалоидной мембраны в патогенезе и хирургии пролиферативной диабетической ретинопатии // Вестник офтальмологии. — 1996. — № 4. — С. 5–8.
  8. Akiba J., Arzabe C. W., Trempe C. L. Posterior vitreous detachment and neovascularization in diabetic retinopathy // Ophthalmology. — 1990. — Vol. 97. — N. 7. — P. 889–891.
  9. Anderson D. H., Mullins R. F., Hageman G. S., Johnson L. V. A role for local inflammation in the formation of drusen in the aging eye // Am. J. Ophthalmol. — 2002. — Vol. 134. — N. 3. — P. 411–431.
  10. Barbazetto I. A. Oxygen tension in the rabbit lens and vitreous before and after vitrectomy // Exp. Eye Res. — 2004. — Vol. 78. — N. 5. — P. 917–924.
  11. Binder S., Glittenberg C., Falkner-Radler C., Krebs I. Influence of Vitreous Traction on AMD // Retina today. — 2009. — October — P. 61–62.
  12. Foos R. Y., Wheeler N. C. Vitreoretinal juncture-synchisis senilis and posterior vitreous detachment // Ophthalmology. — 1982. — Vol. 89. — N. 12. — P. 1502–1512.
  13. Gandorfer A. Pharmacological vitreolysis // Klin. Monbl. Augenheilkd. — 2011. — Vol. 228. — N. 3. — P. 201–207.
  14. Gawecki M., Doroszkiewicz M., Rydzewski J. Age related macular degeneration and presence of posterior vitreous detachment // Klin. Oczna. — 2010. — Vol. 112. — N. 7–9. — P. 210–212.
  15. Green-Simms A. E., Bakri S. J. Vitreomacular traction and age-related macular degeneration // Semin. Ophthalmol. — 2011. — Vol. 26. — N. 3. — P. 137–138.
  16. Gross-Jendroska M., Flaxel C. J., Schwartz S. D. et al. Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection // Aust. N. Z. J. Ophthalmol. — 1998. — Vol. 26. — N. 4. — P. 311–317.
  17. Holekamp N. P., Shui Y. B., Beebe D. C. Vitrectomy surgery increases oxygen exposure to the lens: a possible mechanism for nuclear cataract formation // Am. J. Ophthalmol. — 2005. — Vol. 139. — N. 2. — P. 302–310.
  18. Hyams S. W., Neumann E., Friedman Z. Myopia-aphakia. II. Vitreous and peripheral retina // Br. J. Ophthalmol. — 1975. — Vol. 59. — N. 9. — P. 483–485.
  19. Ikeda T., Sawa H. Pars plana vitrectomy for regression of choroidal neovascularization with age-related macular degeneration // Acta Ophthalmol. Scand. — 2000. — Vol. 78. — N. 4. — P. 460–464.
  20. Jonson M. W. Perifoveal vitreous detachment and its macular complications // Trans. Am. Ophthalmol. Soc. — 2005. — Vol. 103. — P. 537–567.
  21. Johnson M. W. Posterior vitreous detachment: evolution and complications of its early stages // Am. J. Ophthalmol. — 2010. — Vol. 149. — N. 3. — P. 371–382.
  22. Kakehashi A., Kado M., Akiba J., Hirokawa H. Variations of posterior vitreous detachment // Br. J. Ophthalmol. — 1997. — Vol. 81. — N. 7. — P. 527–532.
  23. Krebs I., Brannath W., Glittenberg C. et al. Posterior vitreomacular adhesion: a potential risk factor for exudative age-related macular degeneration? // Am. J. Ophthalmol. — 2007. — Vol. 144. — N. 5. — P. 741–746.
  24. Krebs I., Glittenberg C., Zeiler F., Binder S. Spectral domain optical coherence tomography for higher precision in the evaluation of vitreoretinal adhesions in exudative age-related macular degeneration // Br. J. Ophthalmol. — 2011. — Vol. 95. — N. 10. — P. 1415–1418.
  25. Lambert H. M., Capone A. Jr., Aaberg T. M. et al. Surgical excision of subfoveal neovascular membranes in age-related macular degeneration // Am. J. Ophthalmol. — 1992. — Vol. 113. — N. 3. — P. 257–262.
  26. Lee S. J., Lee C. S., Koh H. J. Posterior vitreomacular adhesion and risk of exudative age-related macular degeneration: paired eye study // Am. J. Ophthalmol. — 2009. — Vol. 147. — N. 4. — P. 621–626.
  27. Maller J., George S., Purcell S. et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration // Nat. Genet. — 2006. — Vol. 38. — N. 9. — P. 1055–1059.
  28. Mojana F., Cheng L., Bartsch D. U. et al. The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results // Am. J. Ophthalmol. — 2008. — Vol. 146. — N. 2. — P. 218–227.
  29. Nomura Y., Ueta T. et al. Vitreomacular Interface in Typical Exudative Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy // Ophthalmology. — 2011. — Vol. 118. — N. 5. — P. 853–859.
  30. Novak M. A. Complications of acute symptomatic posterior vitreous detachment // Am. J. Ophthalmol. — 1984. — Vol. 97. — N. 3. — P. 308–314.
  31. Ochoa-Contreras D., Delsol-Coronado L., Buitrago M. E. Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy // Acta Ophthalmol. Scand. — 2000. — Vol. 78. — N. 6. — P. 687–688.
  32. O'Malley P. The pattern of vitreous syneresis. A study of 800 autopsy eyes. Advances in vitreous surgery. — Springfield. IL. — 1976. — P. 17–33.
  33. Ondes F., Yilmaz G., Acar M. A. et al. Role of the vitreous in age-related macular degeneration // Jpn. J. Ophthalmol. — 2000. — Vol. 44. — N. 1. — P. 91–93.
  34. Ono R., Kakehashi A., Yamagami H. Prospective assessment of proliferative diabetic retinopathy with observations of posterior vitreous detachment // Int. Ophth. — 2005. — Vol. 26. — N. 1–2. — P. 15–19.
  35. Perichon J. Y., Brasseur G., Uzzan J. Ultrasonographic study of posterior vitreous detachment in emmetropic eyes // J. Fr. Ophtalmol. — 1993. — Vol. 16. — N. 10. — P. 538–544.
  36. Pravin U. Dugel. A New Focus on the Vitreous and Its Role in Retinal Function // Retina today. — 2012. — April. — P. 50–53
  37. Pravin U. Dugel. The Evolution of Understanding of Vitreomacular Adhesion // Retina today Supplement. — 2012. — May. — P. 1–4.
  38. Punjab O., Kaiser P. Vitreomacular Adhesion in Exudative Age-related Macular Degeneration // European Ophthalmic review. — 2012. — Vol. 6. — N. 1. — P. 48–50.
  39. Reese A. B., Jones I. S., Cooper W. C. Macular changes secondary to vitreous traction. Am. J. Ophth. — 1967. — Vol. 64. — P. 544–549.
  40. Robison C. D., Krebs I., Binder S. et al. Vitreomacular adhesion in active and end-stage age-related macular degeneration // Am. J. Ophthalmol. — 2009. — Vol. 148. — N. 1. — P. 79–82.
  41. Sakamoto T., Sheu S. J., Arimura N. Vitrectomy for exudative age-related macular degeneration with vitreous hemorrhage // Retina. — 2010. — Vol. 30. — P. 856–864.
  42. Schulze S., Hoerle S., Mennel S., Kroll P. Vitreomacular traction and exudative age-related macular degeneration // Acta Ophthalmol. — 2008. — Vol. 86. — N. 5. — P. 470–481.
  43. Sebag J. Ageing of the vitreous // Eye. — 1987. — N. 1. — P. 254–262.
  44. Sebag J. Anomalous posterior vitreous detachment: a unifying concept in vitreoretinal disease // Graefes Arch. Clin. Exp. Ophthalmol. — 2004. — Vol. 242. — P. 690–698.
  45. Sebag J. Macular holes and macular pucker: the role of vitreoshisis as imaged by optical coherence tomography/scanning laser ophthalmoscopy // Trans. Am. Ophth. Soc. — 2007. — Vol. 105. — P. 121–131.
  46. Sebag J. Classifying posterior vitreous detachment: a new way to look at the invisible // Brit. J. Ophthalmol. — 1997. — Vol. 81. — N. 7. — P. 521–522.
  47. Sebag J. Pharmacologic vitreolysis // Retina. — 1998. — Vol. 18. — P. 1–3.
  48. Sebag J. Surgical Anatomy of Vitreous and the Vitreoretinal Interface. In: Duane’s Clinical Ophthalmology (Tasman W., Jaeger E. A. eds). — Philadelfia: JB Lippincott. — 1994. — Vol. 6. — Chap. 51. — P. 1–24.
  49. Sebag J. The Vitreous: Structure, Function and Pathobiology. — New York, Springer-Verlag. — 1989. — P. 116–120.
  50. Sebag J. Treatment of vitreomacular adhesion // Retina today. — 2012. — April. — P. 55–58.
  51. Sebag J., Wang M. Y., Nguyen D., Sadun A. A. Vitreo-papillary adhesion in macular diseases // Trans. Am. Ophthalmol. Soc. — 2009. — Vol. 107. — P. 35–44.
  52. Seddon J. M., Reynolds R., Maller J. et al. Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables // Invest. Ophthalmol. Vis. Sci. — 2009. — Vol. 50. — N. 5. — P. 2044–2053.
  53. Seko Y., Fujikura H., Pang J. et al. Induction of vascular endothelial growth factor after application of mechanical stress to retinal pigment epithelium of the rat in vitro // Invest. Ophthalmol. Vis. Sci. — 1999. — Vol. 40. — N. 13. — P. 3287–3291.
  54. Snead M. P., Snead D. R., James S., Richards A. J. Clinicopathological changes at the vitreoretinal junction: posterior vitreous detachment // Eye. — 2008. — Vol. 22. — N. 10. — P. 1257–1262.
  55. Spaide R. F., Armstrong D., Browne R. Choroidal neovascularization in age-related macular degeneration: what is the case? // Retina. — 2003. — Vol. 23. — P. 595–614.
  56. Stalmans P., Benz M. S., Gandorfer A. MIVI-TRUST Study Group. et al. Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes // N. Engl. J. Med. — 2012. — Vol. 367. — N. 7. — P. 606–615.
  57. Stefánsson E., Geirsdóttir A., Sigurdsson H. Metabolic physiology in age related macular degeneration // Prog. Retin. Eye Res. — 2011. — Vol. 30. — N. 1. — P. 72–80.
  58. Stefansson E., Landers M. B., Wolbarsht M. L. Increased retinal oxygen supply following pan-retinal photocoagulation and vitrectomy and lensectomy // Tran. Am. Ophth. — 1981. — Vol. 79. — P. 307–334.
  59. Stefansson E., Loftsson T. The Stokes-Einstein equation and the physiological effects of vitreous surgery // Acta Ophthalmol. Scand. — 2006. — Vol. 84. — N. 6. — P. 718–719.
  60. Takahashi M., Trempe S. L., Maguire K. et al. Vitreoretinal relationship in diabetic macular retinopathy // Arch. Ophthalmol. — 1981. — Vol. 99. — N. 2. — Р. 241–245.
  61. Tsui I., Pan C. K., Rahimy E., Schwartz S. Ocriplasmin for Vitreoretinal Diseases // J. Biomed. and Biotech. — 2012. — October. — P. 14.
  62. Uchino E., Uemura A., Ohba N. Initial Stages of Posterior Vitreous Detachment in Healthy Eyes of Older Persons Evaluated by Optical Coherence Tomography // Arch. Ophthalmol. — 2001. — Vol. 119. — P. 1475–1479.
  63. Wang M. Y., Nguyen D., Hindoyan N., Sadun A. A. Vitreo-papillary adhesion in macular hole and macular pucker // Retina. — 2009. — Vol. 29. — N. 5. — P. 644–650.
  64. Weber-Krause B., Eckardt U. Incidence of posterior vitreous detachment in eyes with and without age-related macular degeneration. An ultrasonic study // Ophthalmologe. — 1996. — Vol. 93, N. 6. — P. 660–665.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2013 Dal N.Y., Shaar G.B., Astakhov Y.S., Lobanova M.M.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-65574 от 04 мая 2016 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies