The peculiarities ofpenis elastic fiber inpatients with erectiledysfunction andpeyronie's disease

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Abstract


The aim of this research was to study the morphologic characteristic of penis elastic fibers in patients with
erectile dysfunction (ED) and Peyronies disease (PD) by morphometric methods. Taken material was penis
biopsy of 23 patients with ED and 9 patients with PD. Elastic fibers were tudied with the help of resorcinfuchsin
by Veigerts and Vergofs methods. The qualitative changes of elastic fibers such as bifurcation of
fibers, decolorization, cob formation, fiber thinning combining with structure thickening were detected.
The decreasing of elastic fibers quantity in tunica albuginea and corpus cavernosa of penis in patients with
ED and PD was noted. These elastic fibers can not be considered as physiologic fibers because they dont
make their function. Their malfunction and their increasing in tissue of penis evidently lead to the
deterioration of penis elasticity and erectile disorder

About the authors

V V Klimachev

Email: vitalgerdt14@yandex.ru

A I Neymark

Email: vitalgerdt14@yandex.ru

V Ya Gerval'd

Email: vitalgerdt14@yandex.ru

I P Bobrov

Email: vitalgerdt14@yandex.ru

A M Avdalyan

Email: vitalgerdt14@yandex.ru

M N Myadelets

Email: vitalgerdt14@yandex.ru

H I Muzalevskaya

Email: vitalgerdt14@yandex.ru

I V Gerval'd

Email: vitalgerdt14@yandex.ru

P T Aliev

Email: vitalgerdt14@yandex.ru

M A Kazymov

Email: vitalgerdt14@yandex.ru

V V Klimachev

A I Neimark

V J Gervald

I P Bobrov

A M Avdalyan

M N Myadelets

N I Muzalevskaya

I V Gervald

R T Aliev

M A Kazymov

References

  1. Баканова А.С. Пенильная гемодинамика и микроциркуляция в норме и при васкулогенной эректильной дисфункции: автореф. дис. канд. мед. наук / А.С. Баканова. - Б., 2006. - с
  2. Дмитриев Д.Г. Состояние кавернозной вегетативной иннервации и гемодинамики у больных с фибропластической индурацией полового члена и эректильной дисфункцией / Д.Г. Дмитриев, О.В. Пермякова // Урология. - 2005. - № 5. - С. 40-43
  3. Неймарк А.И. Применение экстракорпоральной ударно-волновой терапии в лечении болезни Пейрони / А.И. Неймарк, Ю.И. Астахов, М.В. Сидор // Урология. - 2004. - № 2. - С. 33-35.
  4. Cavernous Body Reduction in Four Patients with Erectile Dysfunction Due To Insufficient Venous Occlusion and a Deficit of Elastic Fibers in the Tunica Albuginea / Fabrizio Iacono [et al.] // Int. Braz. J. Urol. - 2007. - V. 33, №6. - P. 785-794.
  5. Comparative Study between Corpus Cavernosum-Electromyography Findings and Electron Microscopy of Cavernosal Muscle Biopsies in Erectile Dysfunction Patients / Başar M. Murat [et al.] // Int. J. Urol. - 2007. - V. 5, Is.3. - P. 252-255.
  6. Husain S. Role of PKC and PKC in phenylephrine-induced contraction of rat corpora cavernosa / S. Husain, D. Young, C. J. Wingard // Inter. J. Impot. Res. - 2004. - V. 16. - P. 325-333.
  7. On the pathogenesis of penile venous leakage: role of the tunica albuginea / Ahmed Shafik [et al.] // BMC Urol. - 2007. - V. 7. - 1471-1485. 8. Peyronie's disease / A.J. Bella [et.al.] // J.Sex. Med. - 2007. - V. 4, N6. - P. 1527-1538.
  8. Ultrastructural comparison of penile cavernous tissue between hypertensive and normotensive rats / R. Jiang [et.al.] // Inter. J. Impot. Res. - 2005. - V. 17. - P. 417-423.
  9. Significant Alterations of Serum Cytokine Levels in Patients with Peyronies Disease / P. Reinhold Zimmermann [et al.] // Int. Braz. J. Urol. - 2008. - V.34, N4. - P. 457-466
  10. Thurmond F. Morphology and biomechanics of the microfibrillar network of sea cucumber dermis / F. Thurmond, J. Trotter // J. Exp. Biol. - 1996. - V. 199, N I. 8. - P. 1817-1828.

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Copyright (c) 2010 Klimachev V.V., Neymark A.I., Gerval'd V.Y., Bobrov I.P., Avdalyan A.M., Myadelets M.N., Muzalevskaya H.I., Gerval'd I.V., Aliev P.T., Kazymov M.A., Klimachev V.V., Neimark A.I., Gervald V.J., Bobrov I.P., Avdalyan A.M., Myadelets M.N., Muzalevskaya N.I., Gervald I.V., Aliev R.T., Kazymov M.A.

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