Vol 18, No 1 (2010)


Full intestinal metaplasiagastric mucosa as precancerousconditions: problemspathomorphological diagnosis

Vernigorodskiy S.V., Vernigorodsky S.V.


The results of the survey 27 patients aged 21 to 62 years. Among which were 9 persons with chronic atrophic gastritis and intestinal metaplasia total, 6 of HAG and incomplete, 7 men with moderately differentiated adenocarcinoma of the stomach and the presence of intestinal metaplasia in the surrounding areas (5 mm from the tumor) and 5 persons with unmodified coolant. Conducted general clinical and fibrogastroskopicheskoe study with target biopsy and hromogastroskopiey with 10% acetylcysteine and 1% solution of methylene blue
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):8-11
pages 8-11 views

The peculiarities ofpenis elastic fiber inpatients with erectiledysfunction andpeyronie's disease

Klimachev V.V., Neymark A.I., Gerval'd V.Y., Bobrov I.P., Avdalyan A.M., Myadelets M.N., Muzalevskaya H.I., Gerval'd I.V., Aliev P.T., Kazymov M.A., Klimachev V.V., Neimark A.I., Gervald V.J., Bobrov I.P., Avdalyan A.M., Myadelets M.N., Muzalevskaya N.I., Gervald I.V., Aliev R.T., Kazymov M.A.


The aim of this research was to study the morphologic characteristic of penis elastic fibers in patients with erectile dysfunction (ED) and Peyronies disease (PD) by morphometric methods. Taken material was penis biopsy of 23 patients with ED and 9 patients with PD. Elastic fibers were tudied with the help of resorcinfuchsin by Veigerts and Vergofs methods. The qualitative changes of elastic fibers such as bifurcation of fibers, decolorization, cob formation, fiber thinning combining with structure thickening were detected. The decreasing of elastic fibers quantity in tunica albuginea and corpus cavernosa of penis in patients with ED and PD was noted. These elastic fibers can not be considered as physiologic fibers because they dont make their function. Their malfunction and their increasing in tissue of penis evidently lead to the deterioration of penis elasticity and erectile disorder
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):12-17
pages 12-17 views

Structural characteristicsof musculus sphincterani externus dissectedfrom people ofdifferent ages

Kartashkin V.A., Sapin M.R., Shestakov A.M., Kartashkin V.A., Sapin M.R., Shestakov A.M.


The aim of our study was to investigate the structure, microtopography and quantitative characteristics of musculus sphincter ani externus dissected from people of different ages. It was shown that different parts of musculus sphincter ani externus (subcutaneous, superficial and profound) are characterized by significant morphological differences, particularly associated with the number and size of muscular fascicles separated by thin interlayers of connective tissue. The greatest number of muscular fascicles was found in the subcutaneous part of the sphincter and the lowest number of muscular fascicles was observed in the superficial part of the muscle. We also found that in elderly population this muscle is characterized by the thin muscular fascicles separated by the wide interlayers of connective tissue. According to our data the greatest cross sectional area of muscular fascicles (478 ± 63 μm2) was observed in adolescents and the lowest cross sectional area of muscular fascicles (216 ± 40 μm2) was found in elderly people
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):18-24
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Morphological changesof the gutas the result of acutehemorrhage

Bushurov S.E., Bushurov S.E.


In experiment on rats morphological changes of the gut depending on life expectancy as the result of acute hemorrhage have been studied. During the first day in mucous tunic of the small intestine reduction of its thickness, desquamation and necrosis of villi were marked, in 7,4 % of cases there were erosions and ulcers. The quantity of mast cells with degranulation attributes was increasing from 3 o'clock till 7 o'clock, eosinophilic leukocytes - from 12 o'clock till 24 o'clock. As a result dystrophic changes in ganglion cells of vegetative nervous textures and in smooth muscle cells of a muscle coat led to paresis of the intestine. Changes in the small intestine were characterized by greater expressiveness of dystrophic and necrotic injuries in comparison with the large intestine
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):25-29
pages 25-29 views

Extracellular matrix, angiogenesisand cellular microenvironment atdishormonal hyperplasia, fibroadenomaand breast cancer(Light and electron microscopic study)

Mnikhovich M.V., Ternov M.M., Mniкhovich M.V., Ternov M.M.


The article shows a light and electron microscopic examination of the extracellular matrix, angiogenesis and cellular microenvironment at dishormonal hyperplasia, fibroadenoma and breast cancer. Shown that the extracellular matrix in fibroadenoma and hyperplasia dishormonal different identity changes and is different in breast cancer. Microcirculatory component of breast cancer characterized gistofiziologicheskaya heterogeneity, which manifests the activation of angiogenesis, the relative differentiation of vessels and reg ¬ Ressie individual links microcirculation. Processes stromoobrazovaniya hyperplasia and tumors of the breast associated with the presence of a certain number of macrophages, lymphocytes and plasma cells.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):30-37
pages 30-37 views

Study nature nerve fiberscauses of increasedabbreviations duodenalduring stimulation of the sympatheticnerve

Sveshnikov D.S., Myasnikov V.I., Kuchuk A.V., Trofimova Y.E., Trubetskaya M.A., Sveshnikov D.S., Myasnikov V.I., Kucuk A.V., Trofimova Y.E., Trubetskaya M.A., Smirnov I.L., Smirnov I.L.


In experiments on dogs showed that stimulyatornye reactions induced by electrical stimulation of the sympathetic nerve on the background of a joint blockade of α-adrenergic fentolaminom and β-adrenoceptor propranolol almost completely eliminated lizergolom-blocker S1, 2 receptors. In this introduction lizergola had no significant effects on both the background motor activity of duodenal ulcer, and on the function of the vagus nerve. Concluded that the effector neuron with which realized stimulyatorny phenomenon is serotonin, its effects are carried out with the help of S1, 2 - receptors of smooth muscles
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):38-43
pages 38-43 views

Effect of prolongedalcohol consumption ina free elections in the level of sexhormones

Mkhitarov V.A., Mkhitarov V.A.


In a free choice between 15 -% solution of ethanol and water in a group of 30 male Wistar rats were distinguished 3 groups on the level of alcohol consumption. Body weight was increased in groups with middle and high consumption of ethanol. The content of gonadotropic hormones (LH and FSH) in animals, which consumed the maximum amount of ethanol, compared with controls was reduced, while urovevn testosterone, both general and free, were raised in direct proportion to the total amount of consumed ethanol. Index of ratio of total testosterone increased in proportion to the free consumption of ethanol. Changing the content in the blood serum of gonadotropic and sex hormones were correlated with the level of alcohol consumption
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):44-48
pages 44-48 views

Strengthening theLIPID PEROXIDATION ANDSERUM ALBUMIN compensatoryreactions in patients in therecovery period STROKE

Uzbekov M.G., Alferova V.V., Misionzhnik E.Y., Luk'yanyuk E.V., Gekht A.B., Shklovskiy V.A., Uzbekov M.G., Alferova V.V., Misionzhnik E.Y., Lukyanyuk E.V., Hecht A.B., Shklovskii V.A.


Studied the concentration of malondialdehyde (MDA), an effective (ECA) and total (OCA), the concentration of CA in 30 patients (cf. the age of 69 ± 8 years, 18 women, 12 men) and 17 healthy subjects of comparable age and sex. In 88% of patients with AI showed an increase in MDA compared with the norm (P <0.01). The aim - to define the pathogenetic aspects of the processes of lipid peroxidation (LPO) in blood plasma and functional activity of human serum albumin (SA) patients in the recovery period (4-5 months) ischemic hemispheric stroke (AI). In patients with ischemic activation of LPO pathogenetically associated with a decrease in acceptor ability of the CA. Reduction ECA noted in 80% of patients with ischemic compared with normal (P <0,01). Thus, the recovery period, the AI increased lipid peroxidation is a violation of the functional activity of the CA, which is accompanied by a decrease in compensatory reaction SA.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):49-55
pages 49-55 views

State of lipidmetabolism for the boy,living in the region iodinedeficiency

Shevchuk V.V., Shevchuk V.


The effect of subclinical thyroid function on the lipid spectrum of blood serum of young men living in iodine deficiency region. The study involved 58 adolescents aged 15-18 years. Found that an increase in TSH levels tended to change direction in the atherogenic lipid spectrum, compared with persons with normal TSH. Identify linkages proved to be positive on all counts and the most pronounced between TSH and the level of triglycerides, α-cholesterol, pre-β-cholesterol. Thus, adequate correction of iodine deficiency can be attributed to a number of preventive measures to reduce the incidence of cardiovascular disease.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):56-59
pages 56-59 views

Effects of statines onlysosomal membranespermeability inalloxan diabetes

Polupanov A.S., Yakusheva E.N., Polupanov A.S., Yakusheva E.N.


Paper shows that alloxan diabetes in rats increases labilisation coefficient of lysosomal membranes in liver and skeletal muscle. Lovastatin and simvastatin labilase lysosomal membranes in normal rats and stabilase lysosomal membranes in investigated organs of rats with alloxan diabetes.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):60-65
pages 60-65 views

Comparative efficacy of drugs ofdifferent pharmacotherapeuticgroups in experimental toxichepatitis

Tauki A.N., Fedorov V.N., Kunitsa Z.A., Smirnov N.A., Kochneva N.V., Taouk A.N., Fiodorov V.N., Kunitsa Z.A., Smirnov N.A., Kotshneva N.V.


This article discusses the evaluation of pharmacological effectiveness of drugs of different pharmacotherapeutic groups in an experimental model of toxic hepatitis. The method of two-stage pharmacological screening. Key findings: of immunomodulators were found drugs worsen the condition of the liver against toxic hepatitis, the combination of essential phospholipids and glycyrrhizic acid is substantially more important hepatoprotective activity, in comparison with the effectiveness of this combination of components that are applied separately, the number of members of the group of adaptogens immunostimulant effect of which is the only one component of their actions, have a more pronounced hepatoprotective activity compared with the specialized immunomodulators
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):66-73
pages 66-73 views

Harmonization analysisof hospital formularyand essential drug listsof federative level

Yakusheva E.N., Yakusheva E.N.


The paper characterizes use of harmonization analysis of hospital formulary and Lists of Essential Drugs of Federative level as method gives quality evaluation of drug selection and is recomended for examination.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):74-79
pages 74-79 views

Ways of perfection ofprotection ofreproductive health ofstudents of highereducationalinstitutions

Egorova E.I., Egorova E.I.


In article problems on preservation of reproductive health of students of higher educational institutions in modern conditions are considered. Creation of regional interuniversity student's polyclinic Is offered. Its structure, principles of work and the basic directions of activity are considered
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):80-84
pages 80-84 views

Practical experience ofdevelopment and use ofphilosophy of thecontrol system by theadvisory-diagnosticcenter

Konovalov O.E., Breusov R.A., Konovalov O.E., Breusov R.A.


In the article there is a characteristic of a control system developed and realized in practice as the advisorydiagnostic center of administrative district of the capital, considering managerial process from the logic, psychological, sociological, economic, organizational and ethical points of view can serve. Its essence consists that employees have an opportunity to satisfy the personal needs, working in conditions of the open, confidential mutual relations; completely realizing the knowledge, skills and experience; having an opportunity to play an active role in acceptance of administrative decisions; in the safe administration safe both healthy working conditions and real care of each person.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):85-88
pages 85-88 views

Major trends reproductionChuvash Republic

Yakovleva T.V., Kuz'min V.N., Yakovlev T.V., Kuzmin V.N., Kiselev A.M.


To understanding speakers and level to death-rate россиян is offered increase the temporary borders of the estimation - over 100 years, position nature of the change to birth rate and death-rate with global standard scheme reproducing the population, match importance of the general factor to death-rate with model level of death-rate depending on existing life expectancy, as well as give the forecast on base of the world development
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):89-93
pages 89-93 views

Medical and demographic analysisof reproductive health plans ofurban families

Medvedeva O.V., Medvedeva O.V.


This article presents an analysis of the needs of children of urban families, which, in turn, is one of the most important characteristics of reproductive behaviour. The analysis showed that the number of children, which respondents, regardless of the form of marriage, would like to have if you have the best for this condition, is less than a replacement.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):94-97
pages 94-97 views

To the question onefficiency of renderingassistance to pregnantwomen, lying-in women,women in childbirth andnewbornsin the Penza region

Mysyakov V.B., Konovalov O.E., Mysyakov V.B., Konovalov O.E.


In article the materials characterising increase of efficiency rendered in Penza region akushersko-gynecologic and neonatological of the help to pregnant women, lying-in women, women in childbirth and newborns are presented. It is shown that at the heart of favorable tendencies in health of the specified groups of the population mediko-organizational actions for reorganisation of corresponding health services lie
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):98-102
pages 98-102 views

Study of the cost of thetime nursing staffoffices highly qualified medicalaid

Fomina A.V., Mezenova N.I., Kicha D.I., Belyavskiy A.R., Fomina A.V., Mezenov N.I., Kicha D.I., Bielawski A.R.


The article presents data obtained in the timing of working hours of nursing staff working in offices vysokotehnologichesnoy care. Results are distributed both on activities of nursing staff, taking into account the phases allocated in the course of industrial activity and by type and groups of manipulation (procedures). Accounting for labor costs of nursing staff has enhanced the effectiveness of nursing care and to optimize the workload for nurses.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):103-107
pages 103-107 views

Sanitarian rating ofmedical x-rayapparatus used inhelth care institutionsof the ryazan region

Cherednikova A.A., Ivanov S.I., Cherednikova A.A., Ivanov S.I.


The paper presents the results of studies of X-ray apparatus capabilities according to the type and timing of their use. The studies were made in the period from 2006 to 2008 in health care institutions of the Ryazan Region. According to the date we have got, more defections are found among the items with the timing of use more then 10 years. Most of such defections are registered among dental X-ray apparatus for general purposes.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):108-112
pages 108-112 views

Oxidizing modificationof albumens in plasmaof blood of patients bydiabetes mellitus oftype 2 iin dependence ondegree ofindemnification ofcarbohydrateexchange and durationof diabetes mellitus oftype 2

Zanozina O.V., Shcherbatyuk T.G., Borovkov N.N., Zanozina O.V., Scherbatuc T.G., Borovkov N.N.


Oxidizing stress at diabetes mellitus ( DM) of type 2 characterized by the generation of free radicals, leading, in particular, to oxidizing modification of albumens. It is rotined that modification of albumens takes place and at subcompensation of carbohydrate exchange, however much maximal changes take place at decompensation of DM of type 2 large durations. For the estimation of stage, orientation, expressed of oxidizing stress for the patients of DM of type 2 it is suggested to use different parts of OMB and their correlations. Not enough for indemnification of carbohydrate exchange breaking of vicious circle ( a generation of free radicals is oxidizing modification of albumens is oxidization of lipids - generation of free radicals).
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):113-118
pages 113-118 views

Investigation of some aspect ofpsychic status in patients withcolorectal cancer

Semionkin E.I., Yakovleva N.V., Trushin S.N., Semionkin E.I., Yakovleva N.V., Trushin S.N.


In this study weve evaluated psychic status of men and women with colorectal cancer of 3 and 4 stages before an operation and after it. Weve used Lushers color test, Spielberger test (Spielberger C. D., 1970) to evaluate the situational and personal anxiety level processed by Hanina Y.L. [9] and personal anxiety scale according Tailor. Weve discovered that patients, especially women, had serious stress reaction, had neurologic syndromes and anxiety-depression condition with adaptation disorders.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):119-123
pages 119-123 views

Influence of Individual PsychologicalPeculiarities in SuccessfulLanguage Mastering

Khokhlova L.A., Deryagina L.E., Khokhlova L.A., Deryagina L.E.


Investigation findings of students individual psychological characteristics contributing to successful learning are presented in the paper. Influence of hemispheric peculiarities, types of the higher nervous activity, anxiety level and motivation in language mastering are analyzed, diagnostic parameters and factors of academic achievement prognosis being revealed.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):124-130
pages 124-130 views

Influence of thepsychoemotional stresson the heart rhythmregulation of thefemale students

Devaev N.P., Suvorov V.V., Devaev N.P., Suvorov V.V.


The work demonstrates results got by the cardiorythmography method for the heart rhythm variability analyses. The research work was held in the group of the female students (65 individuals) within the framework of the ordinary working day during the examination session. The average age of the tested persons is 17.25±0.52 years. The analyses of the data has revealed real vegetative nervous system changes in the psycho emotional stress (according to the model of the test variant), that is - increase of the sympathetic part activity and decrease of the parasympathetic part activity
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):131-135
pages 131-135 views

Complex treatment of venoustrophic ulcers and the new conceptof pathogenesis

Shval'b P.G., Shval'b A.P., Gryaznov S.V., Shvalb P.G., Shvalb A.P., Griaznov S.V.


Changing pneumatic compression has a stimulating activity on the processes of regeneration, it stops the condition of stagnation of the trophic ulcer. Unfortunately the frequency of recurrence is not predictable. Venous trophic ulcers have some peculiarities and it makes them different from trophic ulcers of another origin. This is a phenomenon of independent progression of ulcer properties and their exacerbation. Our examinations confirm the view of venous trophic ulcer as a system with closed pseudo chaotic activity, it makes a clinic task: to change the condition of ulcer from the given one to wound with consequences of restoring processes.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):136-142
pages 136-142 views

State uvealblood flow in ischemicdiseases persons witheye in combination withocclusive-stenoticlesions of internalcarotid arteries

Lapshova E.V., Lapshova Е.V.


The study involved 48 people (48 eyes) at 49-76 years of age with acute circulatory disturbances in the arterial system of the organ of vision, including 28 women and 20 men. Hemodynamic parameters of the uveal blood flow by the rheoophthalmography method (ROG) and ultrasound duplex scanning of carotid vessels were studied. The rheoophthalmography method allows doctors to suggest the presence and the degree of ICA stricture formation by the degree of ROG index changing. The early diagnosis of carotid artery pathology will give a chance to approach the treatment subject differentially.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):143-147
pages 143-147 views

The study of elementcontent, free and boundsugars in cucubalusbaccifer and myosotonaquaticum herb

Darmogray S.V., Fursa N.S., Darmogray S.V., Fursa N.S.


The study of C. baccifer and M. aquaticum element content - 7 macro- (Al, Ca, K, Mg, Na, P, Si), 54 micro- and ultramicroelements (Ag, As, Au, B, Ba, Be, Bi, Br, Ce, Co, Cd, Cs, Cu, Dy, Er, Eu, Fe, Ga, Ge, Gd, Hf, Hg, Ho, I, La, Li, Lu, Mn, Mo, Nb, Nd, Ni, Pb, Pr, Rb, Sb, Se, Sm, Sn, Sr, Ta, Tb, Th, Ti, Tl, Tm, U, V, W, Y, Yb, Zn, Zr) was carried out by the method of massspectrometry with inductively coupled plasma, free sugars (glucose, fructose) by HPLC and bound sugars (arabinose, glucose, galactose, xylose) by capillary electrophoresis.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):148-155
pages 148-155 views

The cancer ofbartholin's gland withmetastasis in the brain

Tsygankova L.V., Ryazantsev E.L., Biryukov A.N., Tsygankova L.V., Ryazantsev E.L., Biryukov A.N.


In this article there is a rare case of malignant tumor of vulva, the cancer of Bartholins gland. This case is interested, except the rareness of this disease, by the difficulties which are appeared at the first diagnosis and metastases the malignant tumor in the brain.
I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):156-159
pages 156-159 views

Yu.V. Postnov (1929-2010)

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I.P. Pavlov Russian Medical Biological Herald. 2010;18(1):165-165
pages 165-165 views

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